Patents Assigned to Bond of Regents, The University of Texas System
  • Recombinant human IgA-J chain dimer
    Patent number: 6673342
    Abstract: Disclosed are compositions and methods of use that comprise engineered IgA antibodies that, when administered to a host are secreted across the epithelium into the mucosal barriers of the body providing external passive immunotherapy against agents such as viral, bacterial and eukaryotic pathogens. Also disclosed are mini antibodies comprising the minimal transcytosis domains.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: January 6, 2004
    Assignees: Bond of Regents, The University of Texas System, The United States of America as represented by the Department of Health and Human Services
    Inventors: J. Donald Capra, Jonathan M. Hexham, Leon N. Carayannopoulos, Edward E. Max