Patents Assigned to Bone Support AB
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Patent number: 10994998Abstract: The invention relates to hardenable ceramic bone substitute compositions having improved setting, powders for such compositions and methods for their manufacture and use in medical treatment. More specifically the invention relates to hardenable bone substitute powder and hardenable bone substitute paste with improved setting properties, comprising calcium sulfate and heat-treated hydroxyapatite (passivated HA), which bone substitute is suitable for treatment of disorders of supportive tissue such as bone loss, bone fracture, bone trauma and osteomyelitis.Type: GrantFiled: May 16, 2018Date of Patent: May 4, 2021Assignee: BONE SUPPORT ABInventors: Kristina Caroline Victoria Ehrenborg, Veronica Rebecca Sandell, Eva Christina Lidén
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Patent number: 10294107Abstract: The invention relates to hardenable ceramic bone substitute compositions having improved setting, powders for such compositions and methods for their manufacture and use in medical treatment. More specifically the invention relates to hardenable bone substitute powder and hardenable bone substitute paste with improved setting properties, comprising calcium sulfate and heat-treated hydroxyapatite (passivated HA), which bone substitute is suitable for treatment of disorders of supportive tissue such as bone loss, bone fracture, bone trauma and osteomyelitis.Type: GrantFiled: February 20, 2014Date of Patent: May 21, 2019Assignee: Bone Support ABInventors: Kristina Caroline Victoria Ehrenborg, Veronica Rebecca Sandell, Eva Christina Lidén
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Patent number: 9180137Abstract: A method for the preparation of injectable ready-to-use paste bone cement compositions by mixing a dry inorganic bone cement powder comprising a particulate calcium sulfate hemihydrate capable of hardening in vivo by hydration of the calcium sulfate hemihydrate forming calcium sulfate dihydrate, an aqueous liquid and an additive that normally retards the setting process, said method comprising a) providing a bone cement powder comprising calcium sulfate hemihydrate, an accelerator for the hardening of the calcium sulfate hemihydrate by hydration, said accelerator being selected from the group consisting of saline and calcium sulfate dihydrate, and a powdered calcium phosphate component b) mixing the bone cement powder with the aqueous liquid for a period of time c) leaving the mixture for the time needed for allowing the hydration reaction of the calcium sulfate hemihydrate to proceed and allowing calcium sulfate dihydrate crystals to form and grow, and d) admixing the additive by means of a short-duration mType: GrantFiled: February 8, 2011Date of Patent: November 10, 2015Assignee: BONE SUPPORT ABInventors: Veronica Sandell, Malin Nilsson, Eva Liden, Jeffrey C. Karr
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Publication number: 20140198601Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container (3) has a mixing space (4) in which at least one powder and at least one liquid component (5, 6) are mixed to provide the hardenable mass (2). A piston means (7) is provided in the mixing space (4) of the mixing container (3). At least one means (8) which is rotatable relative to the mixing container (3) cooperates with the piston means (7) for, in a retaining position (P1), retaining said piston means (7) relative to the mixing container (3) and, by rotation to a release position (P2), releasing the piston means (7) such that said piston means can move in a direction (U) towards at least one opening (49) through which said mass (2) can pass out of the mixing space (4).Type: ApplicationFiled: January 16, 2014Publication date: July 17, 2014Applicant: Bone Support ABInventors: Lars LIDGREN, Sven JÖNSSON, Torgny LUNDGREN, Östen GULLWI, Fritz BRORSSON
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Patent number: 8662737Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container may include a mixing space in which at least one powder and at least one liquid component are mixed to provide the hardenable mass. A piston may be provided in the mixing space of the mixing container. A screw device may be connectable to the mixing container such that the screw device may be configured to impart by screw movements a discharge movement to the piston to discharge the hardenable mass from the mixing space.Type: GrantFiled: September 13, 2012Date of Patent: March 4, 2014Assignee: Bone Support ABInventors: Lars Lidgren, Sven Jönsson, Torony Lundgren, Fritz Brorsson, Östen Gullwi
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Patent number: 8586101Abstract: The invention refers to an artificial bone mineral substitute material which comprises at least one ceramic and at least one water soluble non-ionic X-ray contrast agent. The invention refers to a composition for producing the same, which further comprises an aqueous liquid, as well as the use of the composition as a X-ray contrast medium.Type: GrantFiled: December 20, 2002Date of Patent: November 19, 2013Assignee: Bone Support ABInventor: Lars Lidgren
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Publication number: 20130268088Abstract: An injectable bone mineral substitute material composition with the capability of being hardened in a body fluid in vivo, which comprises at least one calcium phosphate component and at least one calcium sulfate component as a dry mixture mixed with an aqueous liquid, and at least one accelerator, the at least one calcium sulfate component being particulate hardened calcium sulfate, which has a specified particle size that is in order to confer injectablity to the composition. The invention also concerns the bone mineral substitute material produced from the composition as well as methods and uses thereof.Type: ApplicationFiled: March 13, 2013Publication date: October 10, 2013Applicant: Bone Support ABInventors: Lars Lidgren, Malin Nilsson
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Patent number: 8420127Abstract: An injectable bone mineral substitute material composition with the capability of being hardened in a body fluid in vivo, which comprises at least one calcium phosphate component and at least one calcium sulfate component as a dry mixture mixed with an aqueous liquid, and at least one accelerator, the at least one calcium sulfate component being particulate hardened calcium sulfate, which has a specified particle size that is in order to confer injectability to the composition. The invention also concerns the bone mineral substitute material produced from the composition as well as methods and uses thereof.Type: GrantFiled: March 5, 2004Date of Patent: April 16, 2013Assignee: Bone Support ABInventors: Lars Lidgren, Malin Nilsson
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Patent number: 8297831Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container (3) has a mixing space (4) in which at least one powder and at least one liquid component (5, 6) are mixed to provide the hardenable mass (2). A piston means (7) is provided in the mixing space (4) of the mixing container (3). At least one means (8) which is rotatable relative to the mixing container (3) cooperates with the piston means (7) for, in a retaining position (P1), retaining said piston means (7) relative to the mixing container (3) and, by rotation to a release position (P2), releasing the piston means (7) such that said piston means can move in a direction (U) towards at least one opening (49) through which said mass (2) can pass out of the mixing space (4).Type: GrantFiled: September 8, 2009Date of Patent: October 30, 2012Assignee: Bone Support ABInventors: Lars Lidgren, Sven Jönsson, Torgny Lundgren, Fritz Brorsson, Östen Gullwi
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Patent number: 7972630Abstract: An injectable bone mineral substitute material composition comprises an inorganic bone cement powder and a biologically compatible oil. The oil is an intermixture with the cement powder at a concentration of less than 10 wt % of the total weight of the composition in order to improve the rheology of the same. In a method of intermixing a powder of an implant material and a biologically compatible oil to a composition the oil is mixed with the powder of implant material at an elevated temperature.Type: GrantFiled: April 10, 2001Date of Patent: July 5, 2011Assignee: Bone Support ABInventor: Lars Lidgren
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Patent number: 7938572Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container (3) has a mixing space (4) in which at least one powder and at least one liquid component (5, 6) are mixed to provide the hardenable mass (2). A piston means (7) is provided in the mixing space (4) of the mixing container (3). At least one means (8) which is rotatable relative to the mixing container (3) cooperates with the piston means (7) for, in a retaining position (P1), retaining said piston means (7) relative to the mixing container (3) and, by rotation to a release position (P2), releasing the piston means (7) such that said piston means can move in a direction (U) towards at least one opening (49) through which said mass (2) can pass out of the mixing space (4).Type: GrantFiled: June 17, 2005Date of Patent: May 10, 2011Assignee: Bone Support ABInventors: Lars Lidgren, Sven Jönsson, Torgny Lundgren, Fritz Brorsson, Östen Gullwi
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Patent number: 7935121Abstract: The present invention relates to a device for providing spongy bone with bone substitute and/or bone reinforcing material, wherein at least one perforating device (4) is provided for making at least one hole (5) in the spongy bone (1) and wherein at least one flushing or rinsing device (6) is provided for flushing or rinsing the hole (5) with a rinsing agent (7). At least one vacuum source (9) is provided for generating a vacuum in the hole (5) in the spongy bone (1) for sucking and/or facilitating insertion or feeding of the bone substitute and/or bone reinforcing material (3) into said spongy bone (1). The invention also relates to bone substitute and/or bone reinforcing material and methods in connection with the invention.Type: GrantFiled: November 10, 2004Date of Patent: May 3, 2011Assignee: Bone Support ABInventors: Lars Lidgren, Torgny Lundgren, Pär Arvidsson, Sven Jönsson
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Patent number: 7846166Abstract: The present invention relates to a device for providing spongy bone with bone substitute and/or bone reinforcing material, wherein at least one perforating device (4) is provided for making at least one hole (5) in the spongy bone (1) and wherein at least one flushing or rinsing device (6) is provided for flushing or rinsing the hole (5) with a rinsing agent (7). At least one vacuum source (9) is provided for generating a vacuum in the hole (5) in the spongy bone (1) for sucking and/or facilitating insertion or feeding of the bone substitute and/or bone reinforcing material (3) into said spongy bone (1). The invention also relates to bone substitute and/or bone reinforcing material and methods in connection with the invention.Type: GrantFiled: November 10, 2004Date of Patent: December 7, 2010Assignee: Bone Support ABInventors: Lars Lidgren, Torgny Lundgren, Pär Arvidsson, Sven Jönsson
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Patent number: 7417077Abstract: The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprise a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing and delivery system for delivery.Type: GrantFiled: July 16, 2001Date of Patent: August 26, 2008Assignee: Bone Support ABInventors: Lars Lidgren, Malin Nilsson
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Publication number: 20070217282Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container (3) has a mixing space (4) in which at least one powder and at least one liquid component (5, 6) are mixed to provide the hardenable mass (2). A piston means (7) is provided in the mixing space (4) of the mixing container (3). At least one means (8) which is rotatable relative to the mixing container (3) cooperates with the piston means (7) for, in a retaining position (P1), retaining said piston means (7) relative to the mixing container (3) and, by rotation to a release position (P2), releasing the piston means (7) such that said piston means can move in a direction (U) towards at least one opening (49) through which said mass (2) can pass out of the mixing space (4).Type: ApplicationFiled: June 17, 2005Publication date: September 20, 2007Applicants: BONE SUPPORT AB, TEG HOLDING S.A.Inventors: Lars Lidgren, Sven Jonsson, Torgny Lundgren, Fritz Brorsson, Osten Gullwi
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Patent number: 6586009Abstract: A method for manufacturing the powder: component for a cement for medical use includes a liquid component containing a polymerizable substance and a powder component containing a plastic substance and an X-ray contrast medium. The liquid component and the powder component are mixed for providing a setting mass which is set to form the cement. In order to prevent the formed cement from releasing particles wearing on articulating or bearing surfaces adjacent ;the point of cementation, a water soluble, non-ionic X-ray contrast medium is mixed with the plastic substance, and for minimizing the risk of damaging the powder component during the sterilization, sterilizing by radiation of the powder component containing the X-ray contrast medium is carried through a negative pressure or in an inert gas atmosphere.Type: GrantFiled: November 21, 2000Date of Patent: July 1, 2003Assignee: Bone Support ABInventor: Lars Åke Alvar Lidgren
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Patent number: 6448315Abstract: The invention relates to a method for the preparation in a reactor of a UHMWPE material doped with an antioxidant, preferably vitamin E.Type: GrantFiled: December 27, 2001Date of Patent: September 10, 2002Assignee: Bone Support ABInventors: Lars Lidgren, Peter Bengtsson, Peter Sj{overscore (o)}vall, Bengt Wesslén