Abstract: A wireless communication system includes a power amplifier (PA) configured to receive a radio frequency (RF) input signal and to produce a PA output signal, the PA output signal being an amplified version of the RF input signal. A sensor subsystem is configured to perform asynchronous statistical sampling of the RF input signal and of the PA output signal and to generate a sensor subsystem output. A controller, in communication with the sensor subsystem, is configured to obtain the sensor subsystem output and to infer performance of the PA, and may control one or more of a plurality of internal PA parameters. The controller may include a neural network processor to associate a particular statistical input/output characterization with a particular inferred performance for the PA. Compared to known approaches, the system is scalable and achieves lower power consumption, and is configured to obtain information about linearity performance.