Abstract: A homogenous sample of identical bispecific antibody determinants, each determinant being composed of two L-H half-molecules linked by disulfide bonds, each L-H half-molecule being specific for a different antigenic determinant and including at least the F(ab') portion of a monoclonal IgG antibody. The bispecific antibody determinants are useful, e.g., in the formation of multilamellar assemblies and enzyme electrodes.
Type:
Grant
Filed:
December 21, 1981
Date of Patent:
April 24, 1984
Assignee:
Boston Biomedical Research Institute, Inc.