Patents Assigned to Boston Children's Hospital
  • Agents that modulate RGMb-neogenin-BMP signaling and methods of use thereof
    Patent number: 11485787
    Abstract: The present invention relates to compositions and methods for the modulation RGMb-Neogenin-BMP signaling.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: November 1, 2022
    Assignees: Dana-Farber Cancer Institute, Inc., Boston Children's Hospital
    Inventors: Rosemarie Dekruyff, Gordon J. Freeman, Dale Umetsu, Sanhong Yu, Yanping Xiao
  • Nanomesh electrode structures and techniques for the formation thereof
    Patent number: 11419535
    Abstract: Techniques and apparatus for bilayer nanomesh techniques for transparent and/or stretchable electrophysiological microelectrodes. The bilayer may include of a metal layer and a low impedance coating both in a nanomesh form. Bilayer nanomesh structures according to some embodiments may provide high transparency, great flexibility, large stretchability, while providing improved electrochemical performance compared with conventional systems. Other embodiments are described.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: August 23, 2022
    Assignees: NORTHEASTERN UNIVERSITY, BOSTON CHILDREN'S HOSPITAL
    Inventors: Hui Fang, Yi Qiang, Kyung Jin Seo, Pietro Artoni, Michela Fagiolini
  • Agents That Modulate Immune Cell Activation and Methods of Use Thereof
    Publication number: 20150299322
    Abstract: The present invention relates to compositions and methods for the immunomodulation mediated by the interaction of PD-L2 and RGMb.
    Type: Application
    Filed: August 2, 2013
    Publication date: October 22, 2015
    Applicants: Dana-Farber Cancer Institute, Inc., Boston Children's Hospital, President and Fellows of Harvard College
    Inventors: Gordon J. Freeman, Arlene H. Sharpe, Yanping Xiao, Loise Francisco, Rosemarie Dekruyff, Dale Umetsu