Abstract: A device includes an anoscope including an elongated hollow member with a longitudinal slot configured to receive tissue in an interior of the hollow member. The device also includes a clip applicator. The clip applicator includes a body slidably received in the slot and jaws at a distal end of the body configured to hold a ligation clip. The clip applicator further includes a plunger slidably coupled to the body configured to actuate the jaws. When the clip applicator is inserted into the slot and the plunger is moved relative to the body, the jaws close and deform the ligation clip from an open position into a closed position around tissue received in the slot.

Abstract: A matter elimination catheter includes a catheter body extending from a catheter proximal portion to a catheter distal portion. The catheter body includes an infusion lumen, an aspiration lumen fluidly isolated from the infusion lumen, and a septum interposed between the infusion and aspiration lumens. A drive shaft is within the infusion lumen and is configured to provide rotation near the catheter distal portion. A guide wire lumen is within the drive shaft, and the infusion lumen, the drive shaft and the guide wire lumen are fluidly separated from the aspiration lumen with the septum. In one example, fluid bearings are formed between one or more of the catheter body and drive shaft or the drive shaft and a guide wire or guide wire liner when supplied with infusion fluid through the infusion lumen.

Abstract: A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled powered direct fluid jet streams emanate from a fluid jet emanatory in the form of robust radially directed fluid jet streams to impinge upon and ablate difficult and strong thrombus and lesions within a blood vessel. Effluent aspiration is controlled by an exhaust regulator in the form of a roller pump, but effluent removal can be assistingly influenced by the fluid pressure associated with the radially directed fluid jet streams.

Abstract: A medical device having multiple degrees of freedom independent of each other. The medical device includes a handle, an end effector, and a tubular section extending between the handle and the end effector. The end effector is configured to be rotated about a first axis extending through the tubular section without rotating the tubular section. And, the tubular section is configured to be rotated about the first axis with the end effector.

Abstract: According to one aspect, a hand assist device may be configured for use with an endoscope. The hand assist device may comprise a body configured to removably couple to a handle of the endoscope. The body may comprise a recess configured to receive the handle of the endoscope. The recess may extend from a proximal end of the body to a distal end of the body. The body may also comprise a palm support portion and a finger support portion proximal to the palm support portion. The body may further comprise a base support portion distal to the palm support portion.

Abstract: A system for treating tissue includes a clip assembly including clip arms movable relative to a channel of a capsule so that the clip arms are movable between a tissue receiving configuration and a tissue clipping configuration. Also, the system includes an applicator releasably coupleable to the clip assembly. The applicator includes a bushing and a control member extending therethrough. The bushing includes deflectable fingers, each of the fingers including an engaging feature at a distal end thereof to engage a corresponding engaging feature of the capsule of the clip assembly and assembled with a pusher element configured to push the fingers to a radially outward position. The pusher element includes a U-shaped portion curving into a channel of the bushing and a longitudinal portion extending distally therefrom. A cam washer is slidable over a length of the control member and positioned distally of the U-shaped portion.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices and systems with control knobs designed for improved usability and ergonomics. For example, the control knobs of the present disclosure may include surface features for improved gripping, surface features for improved perception of medical device orientation within a patient and/or knobs dimensioned for improved thumb reach and reduced torque.

Abstract: A hemostasis valve assembly for use in a medical device. The hemostasis valve assembly may include a main body portion defining an internal cavity, a seal cartridge disposed within the internal cavity, and a low pressure valve assembly positioned within the internal cavity adjacent to the seal cartridge. The low pressure valve assembly may include a first valve member having a first valve body and a second valve member having second valve body. A portion of a distal side of the first valve member may abut at least a portion of a proximal side of the second valve member.

Abstract: A medical device may include a handle assembly having an actuator and a sheath. The sheath may extend between a proximal end and a distal end. The proximal end of the sheath may be coupled with the actuator. The medical device may further include an end-effector moveable relative to the sheath between an extended configuration and a retracted configuration. The end-effector may include a plurality of expandable legs. Each of the plurality of expandable legs may include a plurality of first indicia and a plurality of second indicia. A color of each of the first plurality of indicia may be different than a color of each of the second plurality of indicia.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include an access valve that may be retrieved after implantation. The access valve may include a frame having a lumen, a self-expandable member extending through the lumen, and an elastic membrane extending through the lumen and a second end of the frame to releasably seal the lumen. The access valve may releasably attach to a wall of a patient and releasably seal an opening through the wall. The access valve may be attached to the wall by placing the frame adjacent the wall, extending the self-expandable member through the opening in the wall, and expanding the self-expandable member such that the self-expandable member applies a first force against the wall and a second force opposite the first force against the frame to sandwich the wall between the self-expandable member and the frame.

Abstract: A matter elimination catheter includes a catheter body extending from a catheter proximal portion to a catheter distal portion. The catheter body includes an infusion lumen, an aspiration lumen fluidly isolated from the infusion lumen, and a septum interposed between the infusion and aspiration lumens. A drive shaft is within the infusion lumen and is configured to provide rotation near the catheter distal portion. A guide wire lumen is within the drive shaft, and the infusion lumen, the drive shaft and the guide wire lumen are fluidly separated from the aspiration lumen with the septum. In one example, fluid bearings are formed between one or more of the catheter body and drive shaft or the drive shaft and a guide wire or guide wire liner when supplied with infusion fluid through the infusion lumen.

Abstract: A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled powered direct fluid jet streams emanate from a fluid jet emanatory in the form of robust radially directed fluid jet streams to impinge upon and ablate difficult and strong thrombus and lesions within a blood vessel. Effluent aspiration is controlled by an exhaust regulator in the form of a roller pump, but effluent removal can be assistingly influenced by the fluid pressure associated with the radially directed fluid jet streams.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices and systems with control knobs designed for improved usability and ergonomics. For example, the control knobs of the present disclosure may include surface features for improved gripping, surface features for improved perception of medical device orientation within a patient and/or knobs dimensioned for improved thumb reach and reduced torque.

Abstract: Medical systems and methods for making and using medical systems are disclosed. Example medical systems may include an atherectomy system configured to engage and remove plaque from walls in vessels of a vascular system. The atherectomy system may include a drive shaft, a rotational tip coupled to an end of the drive shaft, a drive mechanism coupled to the drive shaft to rotate the rotational tip, and control configurations to control settings of operational modules of the atherectomy system. The control configurations may be configured to change settings of multiple operational modules of the atherectomy system in response to a single actuation of an actuator to facilitate use of the atherectomy system in a vasculature of a patient.

Abstract: Hemostasis valves and methods for making and using hemostasis valves are disclosed. An example hemostasis valve may include a main body having a proximal end region. A cartridge may be at least partially disposed within the proximal end region. The cartridge including a seal member. The cartridge may have a proximal member, a distal member, and may define a seal holding region. The seal member may have an axial thickness of about 0.04 to about 0.2 inches. The seal member may be secured within the seal holding region by a mechanical bond.

Abstract: In one example, a medical device may include a main shaft extending from a proximal end to a distal end; a first articulation shaft coupled to the distal end of the main shaft; a second articulation shaft coupled to a distal end of the first articulation shaft; a first articulation wire coupled proximate to a distal portion of the first articulation shaft and extending longitudinally through the main shaft and the first articulation shaft; and a second articulation wire coupled proximate to a distal portion of the second articulation shaft and extending longitudinally through the main shaft, the first articulation shaft, and the second articulation shaft.

Abstract: A medical device that includes a handle, a shaft extending distally from the handle, an end effector extending distally from the shaft, and a first actuator coupled to the handle and secured to a first wire. The first wire extends through the shaft, and the first actuator is configured to pivot relative to the shaft to pull the first wire proximally and to deflect the end effector relative to the shaft.

Abstract: A medical device includes a handle, a shaft extending from the handle, and an articulation member integral with or attached to a distal end of the shaft. The articulation member includes a first portion coupled to a second portion, the second portion is receivable in a slot defined by the first portion, and the handle is coupled to each of the first portion and the second portion and to articulate the first portion independently of articulating the second portion.

Abstract: A medical device that includes a handle, a shaft extending distally from the handle, an end effector extending distally from the shaft, a first actuator movably coupled to the handle, and a second actuator movably coupled to the handle. The first actuator is configured to (1) articulate the shaft in response to translating the first actuator in a first direction relative to the handle and the second actuator, and (2) actuate the end effector in response to translating the first actuator in a second direction relative to the handle and the second actuator. The second actuator is configured to (1) articulate the shaft in response to translating the second actuator in the first direction relative to the handle and the first actuator, and (2) actuate the end effector in response to translating the second actuator in the second direction relative to the handle and the first actuator.

Abstract: A medical device that includes a handle, an actuator movably coupled to the handle, a shaft extending distally from the handle, and a sheath including a distal end disposed within the shaft and a proximal end disposed within the handle. The sheath includes a plurality of branches secured to one another at the distal end and separated from one another at the proximal end. The actuator is coupled to each of the plurality of branches at the proximal end of the sheath, and the actuator is configured to move each of the plurality of branches relative to one another to articulate the shaft in a plurality of directions.