Abstract: A tubular implantable prosthesis is formed of porous expanded polytetrafluoroethylene. The tubular prosthesis includes a substantially continuous ePTFE tubular first body and perimetrically non-continuous second tubular body. A circumferentially deformable support structure is interposed between the inner and outer tubular bodies. The second tubular body is formed of a plurality of elongate PTFE strips. The strips are secured to the first body and arranged longitudinally in a non-overlapping relationship. The prosthesis provides for both axial and radial compliance.

Abstract: A substrate, such as a catheter or a guide wire, or a portion of the substrate is provided with a lubricous, hydrophilic abrasion-resistant coating by: (a) coating the substrate with a first aqueous coating composition having an aqueous dispersion or emulsion of a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups capable of reacting with organic acid groups, and drying the coating to obtain a substantially water-insoluble coating layer having excess polyfunctional including functional groups being reactive with organic acid groups remaining; and (b) contacting the dried water-insoluble coating layer with a second aqueous coating composition having an aqueous solution or dispersion of a hydrophilic polymer having organic acid functional groups, a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups capable of reacting with organic acid groups, and drying the combined coating to form an interme