Abstract: An intravascular ultrasound (IVUS) system includes a catheter having a flexible body with an imaging assembly disposed within the flexible body. An ultrasound transducer is coupled to a distal end region of the imaging assembly. A motor drive unit coupled to a proximal end of the imaging assembly includes a stationary portion with a power source generating an AC power signal and a rotating portion configured to rotate with the imaging assembly. A rotary transformer couples the stationary and rotating portions. The rotating portion includes an amplifier electrically coupled to the ultrasound transducer, a rectifier converting the AC power signal to DC power for the amplifier, and transmit/receive switches protecting the amplifier during transmit mode.

Abstract: Example thrombectomy systems are disclosed. An example thrombectomy system includes a thrombectomy catheter including a distal end region and a lumen extending therein, a fluid supply tube extending within the lumen of the thrombectomy catheter, wherein the fluid supply tube includes one or more fluid supply jets and a pressure relief member coupled to the thrombectomy catheter, wherein the pressure relief member is configured to control effluent fluid flow within the lumen of the thrombectomy catheter. Further, actuation of the pressure relief member is configured to relieve pressure in the lumen of the thrombectomy catheter.

Abstract: A method for removing one or more objects or materials from a body lumen includes delivering a tube and an expandable device to the body lumen to a position proximal to the one or more objects or materials. The expandable device is positioned with a lumen of the tube, and the expandable device includes a lumen extending from a distal portion to a proximal portion. The method further includes proximally retracting the tube such that the expandable device remains in the position proximal to the one or more objects or materials, distally advancing the expandable device such that the distal portion of the expandable device at least partially surrounds the one or more objects or materials, at least partially closing a distal end of the expandable device, and moving the expandable device proximally to remove the expandable device and the one or more objects or materials from the lumen.

Abstract: A bipolar electrosurgical device having first and second electrodes which are movable with respect to each other to be positionable in different configuration for operating in different modes. In one configuration, the bipolar electrosurgical device may operate as an electrosurgical cutting device. In another configuration, the bipolar electrosurgical device may operate as an electrocoagulation device. The bipolar electrosurgical device may also operate in further modes without the application of energy thereto. The first electrode may be in the form of a cutting device of an electrosurgical cutting device, and the second electrode may be pivotable with respect to the first electrode.

Abstract: A closure system for sealing an access site in a blood vessel includes a device handle, a catheter assembly, an expandable member coupled to the catheter assembly, and a sealing shaft assembly connected to a source of RF energy. The sealing shaft assembly includes a second shaft portion movably coupled to a first shaft portion. Distal ends of the first and second shaft portions are axially offset in an open configuration. The catheter assembly is disposed between the first and second shaft portions. A method of sealing the access site includes advancing the catheter assembly into the vessel, shifting the expandable member to the deployed configuration, retracting the closure system to engage the expandable member with the vessel, exposing the sealing shaft assembly, actuating the sealing shaft assembly to grasp the vessel, and applying RF energy to the vessel.

Abstract: A stent delivery system includes a handle having a lumen and a stop disposed within the lumen. A stent delivery catheter includes an inner shaft positioned within the handle lumen with its proximal end abutting the stop, and an outer tubular shaft slidably disposed over the inner shaft. The outer tubular shaft is configured to be retracted proximally past the stop. The system enables controlled deployment of self-expanding stents through relative movement between the inner and outer shafts.

Abstract: A medical device including an application device with a first fluid path and a container movably attached to the application device. The container and the application device have a second fluid path therethrough, the container includes an inner chamber that is intermediate proximal and distal portions of the second fluid path, the inner chamber is fluidly isolated from the proximal portion of the second fluid path at a first position of the container, and the inner chamber is fluidly coupled to the proximal and distal portions of the second fluid path at a second position of the container. The first fluid path bypasses the container and the passage of fluid through the first fluid path is separately controllable from the passage of fluid through the second fluid path.

Abstract: A drug delivery balloon (10) has a drug thereon in the form of crystalline particles (12), the drug having a predetermined size distribution. Optionally marker particles (14, 16) are also provided. A texturized coating (18), a cap layer (20) and/or other methods may be used to increase particle loading capacity of the balloon.

Abstract: The invention provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes an elongate shaft having a distal region and a coil disposed along the distal region. The coil is formed from a winding member having a first filar region and a second filar region. The winding member has a first cross-sectional diameter along the first filar region, a second cross-sectional diameter different from the first cross-sectional diameter along the second filar region, a first centroid at a first position along the first filar region and a second centroid at a second position along the second filar region. The first centroid and the second centroid are axially-aligned.

Abstract: The present disclosure provides for the use of voice activated commands to control the operation of an intravascular ultrasound (IVUS) imaging system and/or to control a graphical user interface (GUI) arranged to convey information related to the IVUS images and other data generated by and for controlling the operations performed by the IVUS imaging system.

Abstract: A medical device may comprise a shaft having an inner sheath and an outer sheath, and a handle. The handle may include a housing defining a channel and the housing may be longitudinally fixedly coupled to the outer sheath. The handle may also include an actuator including a proximal grip portion and a plunger extending distally from the grip portion. A distalmost end of the plunger may include a widened portion, and the plunger may be fixedly coupled to the inner sheath. The widened portion may be longitudinally movable within the channel. A distance between a first surface of the housing and a second surface of the housing may define a maximum distance by which the actuator is movable relative to the housing and a maximum distance by which the inner sheath is movable relative to the outer sheath.

Abstract: The disclosure relates to endoscope valves. An example medical valve comprises a valve stem having a distal end, a proximal end, and a lumen extending along a longitudinal axis of the valve stem between a distal aperture and a proximal aperture; and a cap including a stationary portion and a movable portion which is movable relative to the stationary portion and fixed relative to the valve stem and is configured to move between a first configuration and a second configuration; and a lumen seal coupled to the valve stem, where the lumen seal is configured to: fluidically seal the distal aperture when the movable portion is in the first configuration; and permit fluid flow into the distal aperture when the movable portion is in the second configuration.

Abstract: In some aspects, the present disclosure provides multi-arm polymers that comprise a functional core region and three or more polymer arms extending from the functional core region, each polymer arm of the three or more polymer arms comprising a hydrophilic polymer segment, a reactive moiety and a functional moiety, wherein the reactive moiety and the functional moiety are positioned at an end of each polymer arm and are covalently attached to the hydrophilic polymer segment. In some embodiments, the functional core region is an iodinated core region and the functional moiety is an iodinated moiety.

Abstract: A catheter system (100) for treating a treatment site (106) includes a catheter (102), a system console (123) that includes a console connection aperture (148), an energy source (124), one or more energy guides (122A) that receive energy from the energy source (124), and an optoelectrical connector (151) that is coupled to the catheter (102). The optoelectrical connector (151) includes a guide coupling housing (250) that retains at least a portion of each of the energy guides (122A). The guide coupling housing (250) is configured to be selectively mechanically connected to the system console (123) via the console connection aperture (148) so that the energy guides (122A) are adjustably aligned relative to the energy from the energy source (124).

Abstract: Systems and methods for preventing leaks from an endoscope end of a tube set during equipment changes between endoscopic procedures. An illustrative system may comprise a storage case and a cap. The storage case may comprise a base including a plurality of wells, an insert disposed in each well of the plurality of wells, and a lid configured to cover the base. The cap may have a housing extending from a first open end to a second closed end and defining a cavity between the first open end and the second closed end and may be configured to be removably disposed within a well of the plurality of wells.

Abstract: Methods and systems for refilling a container during an endoscopic procedure. An illustrative reservoir may be placed in selective fluid communication with a water bottle. The water bottle may form a fluid tight seal with the reservoir to transfer water from the water bottle to the reservoir. A water storage chamber may be coupled to a first container and/or a second container.

Abstract: Implantable devices formed of materials which are not readily imageable, and which may shift from a delivery configuration to a deployment configuration upon deployment, are delivered and deployed with a deployment/delivery device having sensors generating a signal indicating contact of the delivery/deployment device with tissue to guarantee purchase of the implantable device with tissue upon deployment. The implantable device may be a tissue anchor with talons which shift from a delivery configuration to a deployed configuration. The sensors may be positioned along a distal end of the delivery/deployment device to indicate purchase of the device with tissue, to ensure purchase of the talons with tissue upon deployment. The sensors may include at least three sensors, which may be spaced apart from one another, to indicate full contact of the distal end of the delivery/deployment device with tissue. The sensors may optionally be aligned with the talons.

Abstract: A percutaneous circulatory support device includes an impeller, a motor configured to rotate the impeller to cause blood to flow through the percutaneous circulatory support device, and a controller operably coupled to the motor. The controller is configured to determine a vascular pressure within a patient, a working voltage applied to the motor to cause the motor to rotate the impeller, a working speed of the motor caused by providing the working voltage to the motor, a blood flow parameter based on the vascular pressure, the working voltage, and the working speed, and a cardiac performance parameter based on the blood flow parameter.