Patents Assigned to Boulder BioScience LLC
  • Methods of treating acute coronary syndrome using 3,3?-diindolylmethane
    Patent number: 12527766
    Abstract: Provided herein are methods of enhancing mechanical thrombectomy during endovascular therapy for acute thrombosis using 3,3?-diindolylmethane.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: January 20, 2026
    Assignee: Boulder BioScience LLC
    Inventors: Michael A. Zeligs, Irwin C. Jacobs
  • Compositions and methods for treating non-hemorrhagic closed head injury
    Patent number: 12171745
    Abstract: Provided herein are methods of treating non-hemorrhagic closed head injury (NHCHI) with 3,3?-diindolylmethane or an analog thereof. In one embodiment, NHCHI covers Traumatic Brain Injuries (TBIs) including mild to severe concussion, blast injury due to proximity to explosions, cerebral contusion, coup-contrecoup injury, DAI, Second Impact Syndrome, or CHI associated with deceleration injury.
    Type: Grant
    Filed: September 27, 2023
    Date of Patent: December 24, 2024
    Assignee: Boulder BioScience LLC
    Inventors: Michael A. Zeligs, Irwin C. Jacobs
  • Methods for improved endovascular thrombectomy using 3,3?-diindolylmethane
    Patent number: 11980604
    Abstract: Provided herein are methods of enhancing mechanical thrombectomy during endovascular therapy for acute thrombosis using 3,3?-diindolylmethane.
    Type: Grant
    Filed: November 9, 2022
    Date of Patent: May 14, 2024
    Assignee: Boulder BioScience LLC
    Inventors: Michael A. Zeligs, Irwin C. Jacobs
  • Methods for improved endovascular thrombectomy using 3,3?-diindolylmethane
    Patent number: 11529331
    Abstract: Provided herein are methods of enhancing mechanical thrombectomy during endovascular therapy for acute thrombosis using 3,3?-diindolylmethane.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: December 20, 2022
    Assignee: Boulder BioScience LLC
    Inventors: Michael A. Zeligs, Irwin C. Jacobs