Patents Assigned to Boyce Thompson Institute
  • COMPOSITIONS AND METHODS USEFUL FOR THE REGULATION OF ABIOTIC STRESS RESPONSES IN HIGHER PLANTS
    Publication number: 20240084321
    Abstract: Compositions and methods for creating plants exhibiting enhanced resistance to abiotic stresses, especially cold stress are disclosed.
    Type: Application
    Filed: November 17, 2023
    Publication date: March 14, 2024
    Applicant: Boyce Thompson Institute for Plant Research, Inc.
    Inventors: David Stern, Coralie Evelyn Salesse-Smith, Leila Feiz
  • Compositions and methods useful for the regulation of abiotic stress responses in higher plants
    Patent number: 11859194
    Abstract: Compositions and methods for creating plants exhibiting enhanced resistance to abiotic stresses, especially cold stress are disclosed.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: January 2, 2024
    Assignee: Boyce Thompson Institute for Plant Research, Inc.
    Inventors: David Stern, Coralie Evelyn Salesse-Smith, Leila Feiz
  • Compositions and methods for modulating immunity in plants
    Patent number: 11849688
    Abstract: Compositions and methods for enhancing disease resistance in plants are disclosed.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: December 26, 2023
    Assignee: Boyce Thompson Institute for Plant Research, Inc.
    Inventors: Daniel F. Klessig, Frank Schroeder, Patricia Manosalva
  • Utility of nematode small molecules
    Patent number: 11673908
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: June 13, 2023
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • Ascaroside treatment of eosinophilic esophagitis
    Patent number: 11464810
    Abstract: A method of preventing or treating eosinophilic esophagitis (EoE) comprising administering a composition comprising ascr#7 is described.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: October 11, 2022
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • Ascaroside treatment of autoimmune and inflammatory diseases
    Patent number: 11077151
    Abstract: The present invention relates to the use of ascr #7 for preventing or treating IL-6 and/or IL-1?-mediated diseases.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 3, 2021
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • Compositions and methods for modulating immunity in plants
    Patent number: 11019776
    Abstract: Compositions and methods for enhancing disease resistance in plants are disclosed.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: June 1, 2021
    Assignee: BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC.
    Inventors: Daniel Klessig, Frank Schroeder, Patricia Manosalva
  • Flagellin-sensing 3 (‘FLS3’) protein and methods of use
    Patent number: 10557145
    Abstract: One aspect of the present invention relates to a nucleic acid construct that includes a nucleic acid molecule that encodes FLAGELLIN-SENSING 3 (“FLS3”) protein; a 5? heterologous DNA promoter sequence; and a 3? terminator sequence, where the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the nucleic acid molecule. The present invention also relates to a method of imparting disease resistance to a plant. This method involves transforming a plant or a plant seed with a nucleic acid molecule that increases expression of an FLS3 protein, where said transforming is effective in imparting disease resistance to the transformed plant or to a transgenic plant produced from the transformed plant seed.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: February 11, 2020
    Assignee: BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC.
    Inventors: Gregory B. Martin, Sarah R. Hind, Susan R. Strickler
  • Compositions and Methods of Increasing Aphid Resistance in Transgenic Plants
    Publication number: 20190390220
    Abstract: The present invention relates to isolated resistance genes encoding polypeptides that confers resistance to aphid infestation, and methods of transforming plant and cells with the disclosed resistance genes. The invention also relates to transgenic plants and cells having resistance to aphids, particularly Aphis glycines.
    Type: Application
    Filed: February 6, 2019
    Publication date: December 26, 2019
    Applicant: Boyce Thompson Institute
    Inventors: Georg Jander, Jing Wei
  • Utility of nematode small molecules
    Patent number: 10479813
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: November 19, 2019
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • Utility of nematode small molecules
    Patent number: 10183963
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: January 22, 2019
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • Compositions and methods for modulating immunity in plants
    Patent number: 10136595
    Abstract: Compositions and methods for enhancing disease resistance in plants are disclosed.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: November 27, 2018
    Assignee: Boyce Thompson Institute for Plant Research, Inc.
    Inventors: Daniel Klessig, Frank Schroeder, Patricia Manosalva
  • Compositions and methods for increasing methionine content in plants
    Patent number: 9879273
    Abstract: Compositions and methods are provided for increasing methionine content in plants are disclosed.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: January 30, 2018
    Assignee: Boyce Thompson Institute for Plant Research, Inc.
    Inventors: Georg Jander, Tengfang Huang, Vijay Joshi
  • Utility of nematode small molecules
    Patent number: 9868754
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: January 16, 2018
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • Small molecule compounds that control plant- and insect-pathogenic nematodes
    Patent number: 9534008
    Abstract: The present invention relates to methods of modifying nematode behavior using certain isolated modulator compounds. Also disclosed are methods of promoting or inhibiting reproduction in a nematode population, methods of promoting or inhibiting nematode aggregation at a first location, and methods of treating or preventing parasite infection of a plant.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: January 3, 2017
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research, The United States of America, As Represented by the Secretary of Agriculture
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss, Fatma Kaplan, Peter A. Teal, Hans Alborn
  • Small molecule compounds that control mammal-pathogenic nematodes
    Patent number: 9487551
    Abstract: The present invention relates to methods of modifying nematode behavior using certain isolated modulator compounds. Also disclosed are methods of promoting or inhibiting reproduction in a nematode population, methods of promoting or inhibiting nematode aggregation at a mammal, and methods of treating or preventing parasite infection of a mammal.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: November 8, 2016
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research, The Regents of the University of California
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss, Raffi V. Aroian
  • Small molecule compounds for the control of nematodes
    Patent number: 9445596
    Abstract: The present invention relates to compounds involved in nematode signaling.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: September 20, 2016
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Frank C. Schroeder, Stephan H. von Reuss, Andrea Choe, Paul W. Sternberg
  • Delayed fruit deterioration allele in plants and methods of detection
    Patent number: 9150623
    Abstract: Disclosed is an isolated nucleic acid molecule comprising a nucleotide sequence that is at least 90% identical to a nucleotide sequence encoding a protein having the amino acid sequence of SEQ ID NO 4, wherein the protein has an aspartic acid (Asp) at amino acid position 106 Transgenic plants comp?sing the nucleic acid have reduced or delayed softening and detenoration of fruit compared to wild-type plants Methods of genetic screening for plants having reduced or delayed softening and detenoration of fruit, isolated oligonucleotides, and a method of imparting to a plant the dfd trait are also disclosed.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: October 6, 2015
    Assignees: Cornell Research Foundation, Inc., Boyce Thompson Institute for Plant Research
    Inventors: Jocelyn Kenneth Rose, Tal Isaacson-Lustig, Julia Vrebalov
  • Enhancement of beta-carotene content in plants
    Patent number: 9115338
    Abstract: The present invention relates to a nucleic acid construct having a nucleic acid molecule configured to silence ?-carotene hydroxylase expression, and host cells, expression systems, plants, and plant seeds having the nucleic acid construct. The present invention also relates to a method of enhancing beta-carotene content by growing a transgenic plant from a plant or seed transformed with the construct.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: August 25, 2015
    Assignees: Boyce Thompson Institute for Plant Research, The United States of America, as represented by the Secretary of Agriculture
    Inventors: Joyce Van Eck, David F. Garvin
  • Baculoviruses with enhanced virion production and a method for the production of baculoviruses
    Patent number: 8961951
    Abstract: The present invention provides a method for restoring budding capability to GP64null baculoviruses including gp64null AcMNPV by expressing therein a portion of the VSV G protein gene or a truncated “stem” portion of the GP64 gene. Other embodiments provide methods to use portions of the G-stem or GP64 protein to target foreign proteins for display on virions.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: February 24, 2015
    Assignee: Boyce Thompson Institute for Plant Research
    Inventors: Gary Blissard, Jian Zhou