Patents Assigned to Bracco Imaging S.p.A.
  • Process for the recovery of copper from aqueous solutions containing iodinated organic compounds
    Patent number: 6827856
    Abstract: The present invention relates to a process for recovering copper from solutions from the recovery of iodine from industrial wastes from the production of ionic and non-ionic iodinated X-ray contrast agents by use of chelating resins suitable for removing copper from aqueous solutions. The absorbed copper is displaced by treating the resins with a 10% hydrochloric or sulfuric acid solution.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: December 7, 2004
    Assignee: Bracco Imaging S.p.A.
    Inventors: Nicola Desantis, Salvatore Incandela
  • Bile acids conjugates with metal ion chelates and the use thereof
    Patent number: 6803030
    Abstract: Compounds able to chelate paramagnetic metal ions and the use thereof as contrast agents in the technique known as “Magnetic Resonance Imaging” (M.R.I.).
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: October 12, 2004
    Assignee: Bracco Imaging S.p.A.
    Inventors: Christoph De Haen, Andrea Beltrami, Enrico Cappelletti, Luciano Lattuada, Mario Virtuani
  • Process for the preparation of iopamidol
    Patent number: 6803485
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: October 12, 2004
    Assignee: Bracco Imaging S.p.A.
    Inventors: Richard A. Lorenzini, Ashok V. Bhatia, Steven A. Chamberlin, Keith A. Drengler, John J. Hufnagel, Xiu C. Wang
  • Bile acid salts
    Patent number: 6479681
    Abstract: A process for the preparation of the compounds of general formula (I) in which R1 is H or OH; R2 is H, &agr;-OH, or &bgr;-OH; and R3 is a straight or branched C1-C4 alkyl group or a benzyl group, comprising the reduction of compounds of formula (III) wherein R1, R2 and R3 have the same meanings as in formula I, in the presence of sodium borohydride.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: November 12, 2002
    Assignee: Bracco Imaging S.p.A.
    Inventors: Marino Brocchetta, Chiara Gallotti, Massimo Visigalli, Pier Lucio Anelli
  • Use of bile acid conjugates, derivatives thereof with metal complexes as blood pool agents for nuclear magnetic resonance diagnostics
    Patent number: 6461588
    Abstract: Blood pool imaging contrast agents containing paramagnetic bi- and tri-valent metal ion chelates of bile acid conjugates with molecules having chelating activity are used in magnetic resonance imaging of the vascular system and particularly the coronaries.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: October 8, 2002
    Assignee: Bracco Imaging S.p.A.
    Inventors: Pier Lucio Anelli, Marino Brocchetta, Christoph De Haen, Ornella Gazzotti, Luciano Lattuada, Giovanna Lux, Giuseppe Manfredi, Pierfrancesco Morosini, Daniela Palano, Michele Serleti, Fulvio Uggeri, Massimo Visigalli
  • Device and method for the regeneration of mixed ion exchange resin beds
    Patent number: 6437010
    Abstract: A method for desalination of water or of aqueous solutions derived from industrial process that use two columns: the first treatment column containing a mixed bed of ion exchange resins, in which the cation exchange resins are regenerated, and a second column, into which the anion exchange resins are transferred and regenerated, to be then reintroduced from the bottom into the above mentioned first column, where they rise through the cation exchange resins.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: August 20, 2002
    Assignee: Bracco Imaging S.p.A.
    Inventors: Carlo Felice Viscardi, Marina Ausonio, Mauro Parenti
  • Process for the preparation of S-N,N?-bis [2-hydroxy-1-(hydroxymethyl) ethyl]-5- [(2-hydroxy-1-oxopropyl) amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
    Patent number: 6350908
    Abstract: A process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide, comprising the reaction of S-(−)-5-[[2-(acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxylic acid dichloride (III) with 2-amino-1,3-propanediol (serinol) without a solvent, followed by hydrolysis of the acetate group.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: February 26, 2002
    Assignee: Bracco Imaging S.p.A
    Inventors: Nicola Desantis, Ilaria Peretto
  • Chelated complexes of paramagnetic metals with low toxicity
    Patent number: RE38329
    Abstract: Compounds of formula (I) and (II) wherein the R, R1, R2, R3 and R4 groups have the meanings defined in the disclosure, are useful chelants for metal ions. The complexes of compounds (I) and (II) with paramagnetic ions are useful as contrast agents for M.R.I. imaging.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: November 25, 2003
    Assignee: Bracco Imaging S.p.A.
    Inventors: Fulvio Uggeri, Franco Fedeli, Alessandro Maiocchi, Maurizio Franzini, Mario Virtuani