Patents Assigned to Bracco S.p.A.
  • Patent number: 10238615
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: March 26, 2019
    Assignee: Bracco S.P.A.
    Inventors: Livio Cavalieri, Giovanni Rivolta, Fulvia Vella
  • Publication number: 20170007563
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Application
    Filed: September 21, 2016
    Publication date: January 12, 2017
    Applicant: Bracco S.P.A.
    Inventors: Livio Cavalieri, Giovanni Rivolta, Fulvia Vella
  • Patent number: 9468619
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: October 18, 2016
    Assignee: Bracco S.P.A.
    Inventors: Aldo Pinchera, Livio Cavalieri, Federico Maisano, Giovanni Rivolta, Ferruccio Santini, Fulvia Vella
  • Patent number: 9439883
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: September 13, 2016
    Assignee: Bracco S.P.A.
    Inventors: Aldo Pinchera, Livio Cavalieri, Federico Maisano, Giovanni Rivolta, Ferruccio Santini, Fulvia Vella
  • Patent number: 9044441
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: June 2, 2015
    Assignee: Bracco S.P.A.
    Inventor: Federico Maisano
  • Publication number: 20130146502
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Application
    Filed: January 31, 2013
    Publication date: June 13, 2013
    Applicant: BRACCO S.P.A.
    Inventor: BRACCO S.P.A.
  • Publication number: 20120087902
    Abstract: The involvement of intestinal microbiota in the initiation and perpetuation of inflammatory bowel disease is widely accepted. To reestablish the homeostasis of the gut the use of probiotics has been proposed, with however, limited clinical benefit. This invention relates to an assay based on the modulation of the immunological activity in DCs (dendritic cells) by probiotic strains, in particular L. paracasei and their use in protecting against inflammatory bowel and liver diseases.
    Type: Application
    Filed: July 20, 2010
    Publication date: April 12, 2012
    Applicant: BRACCO S.P.A.
    Inventors: Maria Rescigno, Carmelina Loguercio, Enzo Grossi
  • Publication number: 20110245342
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 6, 2011
    Applicant: Bracco S.p.A.
    Inventors: Aldo PINCHERA, Ferruccio Santini, Giovanni Rivolta, Livio Cavalieri, Fulvia Vella, Federico Maisano
  • Patent number: 7807395
    Abstract: A method for the laboratory determination of prosthetic infections is described. This method, performed on biological fluids isolated from patients, is based on the detection of antibodies specific for the polysaccharides produced by bacteria colonizing prosthetic devices.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: October 5, 2010
    Assignee: BRACCO S.p.A.
    Inventors: Maria Cristina Thaller, Gianmaria Rossolini, Laura Selan, Claudio Passariello
  • Patent number: 7214794
    Abstract: The present invention is directed to ceramide analog compounds of general formula (I) the process for their preparation and use for the preparation of pharmaceutical formulations for the treatment of tumors
    Type: Grant
    Filed: August 17, 2004
    Date of Patent: May 8, 2007
    Assignee: Bracco S.p.A.
    Inventors: Bruno Macchia, Aldo Balsamo, Marco Macchia, Mario Del Tacca, Romano Danesi
  • Publication number: 20050272816
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations thereof.
    Type: Application
    Filed: November 11, 2003
    Publication date: December 8, 2005
    Applicant: Bracco S.p.A.
    Inventors: Aldo Pinchera, Ferruccio Santini
  • Patent number: 6956109
    Abstract: The present invention is directed to ceramide analog compounds of general formula (I) the process for their preparation and use for the preparation of pharmaceutical formulations for the treatment of tumors.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: October 18, 2005
    Assignee: Bracco S.p.A.
    Inventors: Bruno Macchia, Aldo Balsamo, Marco Macchia, Mario Del Tacca, Romano Danesi
  • Patent number: 6509324
    Abstract: Compounds able to chelate bi- and trivalent paramagnetic metal ions, their chelated complexes with these metal ions and physiologically compatible salts thereof and therein magnetic resonance imaging.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: January 21, 2003
    Assignee: Bracco S.p.A.
    Inventors: Maurizio Franzini, Andrea Beltrami, Luisella Calabi, Alessandro Maiocchi, Mario Virtuani, Pier Lucio Anelli, Kondareddiar Ramalingam, Ramachandran S. Ranganathan
  • Publication number: 20020197280
    Abstract: A method for the laboratory determination of prosthetic infections is described. This method, performed on biological fluids isolated from patients, is based on the detection of antibodies specific for the polysaccharides produced by bacteria colonizing prosthetic devices.
    Type: Application
    Filed: May 1, 2002
    Publication date: December 26, 2002
    Applicant: Bracco S.p.A.
    Inventors: Maria Cristina Thaller, Gianmaria Rossolini, Laura Selan, Claudio Passariello
  • Patent number: 6321105
    Abstract: A method for Magnetic Resonance Imaging (MRI) of changes in neurotransmitter and neuroreceptor activity as a metabolic response to diagnostic challenge or therapeutic treatment in a patient with suspected or already diagnosed mental illnesses of psychiatric, neurodegnerative or neurological nature, by (a) administering to a patient a drug eliciting an MRI detectable hemodynamic response; (b) administering to the patient an MRI contrast agent with high magnetic susceptibility, and then (c) measuring, in a spatially and temporally resolved manner, relative Cerebral Blood Volume (rCBV) changes associated to neuronal activation using T2- or T2*-weighted MRI scans at the equilibrium distribution of said contrast agent.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: November 20, 2001
    Assignee: Bracco S.p.A.
    Inventors: Bruce G. Jenkins, Joe B. Mandeville, Friedrich M. Cavagna
  • Patent number: 5626832
    Abstract: Injectable aqueous composition intended for opacifying certain organs with a view to examination by X-rays. This composition is based on liposomes containing, encapsulated thereein, an aqueous solution of an iodinated opacifying agent. The ratio between the weight of iodine encapsulated by the liposomes and the weight of the lipids from which their membrane is formed is not lower than 1.5 mg/mg.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: May 6, 1997
    Assignee: Bracco S.p.A.
    Inventors: Michel Schneider, Herv e Tournier, Bernard Lamy
  • Patent number: 5599931
    Abstract: The (6S) stereoisomer of folinic acid is obtained in high optical purity by salification of (R,S) folinic acid with di- or polyamines and subsequent selective crystallization of the desired diasteromeric salt.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: February 4, 1997
    Assignee: Bracco S.p.A.
    Inventors: Giorgio Ripa, Rodolfo Piva, Ernst Fekder
  • Patent number: 5380281
    Abstract: The device comprises a tubular housing with two jackets and a container filled with the liquid component of a drug. Within the inner jacket of the housing, close to the closed end thereof, is a chamber containing the powdered components of a drug. A needle for piercing the stopper which closes the container enables the interior of the container to be put in communication with the chamber so as to allow the liquid component to flow out and consequently mix with the powdered component. The subsequent advance of the container into the housing, with the consequent penetration of the piston into the container, causes the further flow of the liquid component into the chamber carrying the drug solution to the exterior of the device generally like a syringe. Its use as a supplier of infusions is also foreseen.
    Type: Grant
    Filed: January 13, 1994
    Date of Patent: January 10, 1995
    Assignee: BRACCO, S.p.A.
    Inventors: Giorgio Tomellini, Gian A. Rollandi
  • Patent number: 5368839
    Abstract: Diagnostic compositions particularly useful for NMR imaging of the gastrointestinal tract, comprise physiologically acceptable aqueous suspensions of insoluble salts of lanthanides, buffered, if required, at a pH value between 6.0 and 8.5 and which are, if required, formulated with appropriate insoluble organic or inorganic additives and/or with dispersing agents, suspending agents or viscosity-enhancing agents. These compositions are capable of increasing the value of the r.sub.2 /r.sub.1 ratio, in which r.sub.1 and r.sub.2 are the longitudinal and transversal relaxivities of the protons of the surrounding water, thus permittting the production of clear images which have negative contrast and which lack artefacts of metallic type.
    Type: Grant
    Filed: November 6, 1992
    Date of Patent: November 29, 1994
    Assignee: Bracco S.p.A.
    Inventors: Silvio Aime, Mauro Botta