Abstract: A method of preparing a first geometric isomer of tamoxifen or an analogue comprises allowing the first isomer to crystallize in hexanol and the product thereof to crystallize in methanol and then derivatising the product of the methanol crystallization to prepare said first isomer in very high purity.
Type:
Grant
Filed:
July 20, 1998
Date of Patent:
January 9, 2001
Assignee:
Bradford University
Inventors:
John Double, Derek Maitland, Ioana Popa
Abstract: A method and apparatus for separating the components of an emulsion comprising an electrically conductive component dispersed in a continuous phase of a substantially electrically insulating component, for instance, a water-in-oil emulsion. The method includes the steps of introducing bubbles of an electrically insulating gas into the emulsion, whilst simultaneously applying an electric or electrostatic field across the emulsion.