Patents Assigned to BRAIN & BEYONDS CO., LTD.
  • Publication number: 20260337052
    Abstract: The present invention relates to a method for preparing superparamagnetic nanoparticles for immunotherapy. Superparamagnetic nanoparticles prepared by the preparation method of the present invention exhibit stable magnetic-induced heating characteristics and high biocompatibility, and thus can be applied through in vivo injection, and induce an increase in immunocytes so as to be effectively used in the treatment of cancer and immune diseases.
    Type: Application
    Filed: August 11, 2023
    Publication date: October 29, 2026
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BRAIN & BEYONDS CO., LTD.
    Inventors: Sun Ha PAEK, Pyung Won IM, Soon Beom PARK
  • Publication number: 20260335359
    Abstract: The present invention relates to a composition for cancer immunotherapy, comprising superparamagnetic nanoparticles as an active ingredient, a composition for treating immune diseases, a composition for enhancing immunity, a composition for suppressing a decrease in immune function or enhancing immune function, the composition being administered in combination with a chemotherapeutic anticancer drug, a composition for suppressing a decrease in immune function, caused by anticancer treatment or enhancing immune function, and a composition for ameliorating, treating or preventing decreased immune responses in individuals with cancer. The superparamagnetic nanoparticles according to the present invention have magnetically-induced heating characteristics and high biocompatibility, thus being applicable through in vivo injection, and can induce an increase in immune cells, thus being effectively used in the treatment of cancer and immune diseases.
    Type: Application
    Filed: August 11, 2023
    Publication date: October 29, 2026
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BRAIN & BEYONDS CO., LTD.
    Inventors: Sun Ha PAEK, Soon Beom PARK
  • Publication number: 20260097212
    Abstract: According to a deep brain stimulation device and a control method thereof according to one embodiment of the present invention, two electrodes are inserted into a deep brain nucleus and supplied with high-frequency current in order to treat brain and neural diseases such as Parkinson's disease, tremor, myodystonia, Alzheimer's dementia, epilepsy, obsessive compulsive disorder, depression, pain, drug addiction, and post-traumatic syndrome, wherein the two electrodes are not supplied with current at the same time, thus making it possible to extend the life of a battery while achieving treatment effects that are the same as or superior to the prior art.
    Type: Application
    Filed: August 11, 2023
    Publication date: April 9, 2026
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BRAIN & BEYONDS CO., LTD.
    Inventors: Sun Ha PAEK, Soon Beom PARK
  • Publication number: 20250255879
    Abstract: The present disclosure provides a pharmaceutical composition comprising a NUPR1 isoform A inhibitor as an active ingredient. Pharmaceutical compositions comprising an NUPR1 isoform A inhibitor may be used in methods of preventing or treating cancer, in methods of diagnosing or predicting prognosis of cancer comprising an agent for measuring an expression or activity level of a NUPR1 isoform A, in a kit for diagnosing or predicting prognosis of cancer comprising the composition, methods for screening a substance for inhibiting cancer cell proliferation or metastasis, methods for providing information for cancer cell proliferation or metastasis, in food compositions for preventing or improving cancer comprising a NUPR1 isoform A inhibitor as an active ingredient, and in feed compositions for preventing or improving cancer comprising a NUPR1 isoform A inhibitor as an active ingredient.
    Type: Application
    Filed: April 2, 2025
    Publication date: August 14, 2025
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BRAIN & BEYONDS CO., LTD.
    Inventors: Sun Ha PAEK, Yona KIM, Ji Hyeon YOU, Soon Beom PARK
  • Publication number: 20250176831
    Abstract: A magnetic resonance imaging (MRI)-based alternating magnetic field (AMF) treatment system according to one embodiment of the technical idea of the present invention comprises an MRI device including an MRI coil system, and is configured to generate an AMF by applying an alternating current to the MRI coil system in the MRI device.
    Type: Application
    Filed: February 13, 2025
    Publication date: June 5, 2025
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BRAIN & BEYONDS CO., LTD., KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Sun Ha PAEK, Zang Hee CHO, Young Don SON, Dae Hyuk KWON, Soon Beom PARK
  • Patent number: D984970
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: May 2, 2023
    Assignee: BRAIN & BEYONDS CO., LTD.
    Inventor: Seongil Lee