Abstract: A method and system to determine brain stiffness is disclosed. A probe to measure tissue water content is inserted through an aperture (burr hole) in the cranium into brain tissue. The probe has two electrically separated plate conductors with a dielectric which forms a capacitor plane. One conductor has a surface mount resistor to allow exact impedance matching to the core of a coaxial cable. The other conductor attaches electrically to the shield of the coaxial cable. The probe is stabilized in the brain tissue through a plastic ventriculostomy bolt which has been secured by screw tapping into the cranium. The coaxial cable connects to a spectrum analyzer. Brain water content and blood congestion alter the resonant frequency of the probe, allowing a realtime readout of apparent tissue water content.

Abstract: A guidance system for guiding a surgical instrument without visual information to a target in tissue. The system centers the target upon the trajectory of an infinite family of zero-flux curvilinear lines emanating from either a fixed magnet or an ac or dc electromagnet which is mounted on the instrument. The approach to the target allows selection of straight and curved trajectories based on the zero-flux lines that intersect the target. A self-centering attachment that holds the magnet allows any straight instrument to be guided by the system. The zero-flux lines are measured by a magnetometer that is located on a remote location on or in the tissue. The transducers of the magnetometer measure the magnetic field strength that is present if the instrument deviates from the zero-flux line. The guidance information is plotted on a display that allows a user to guide the instrument along the zero-flux line to the target.