Patents Assigned to BrainCells Inc
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Publication number: 20110319386Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on muscarinic receptor modulation, such as via inhibition of acetylcholine esterase (AChE) activity, alone or in combination with another neurogenic agent to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: June 10, 2011Publication date: December 29, 2011Applicant: BrainCells Inc.Inventors: Carrolee Barlow, Todd A. Carter, Kai Treuner, Michael Lee
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Publication number: 20110269717Abstract: The instant invention describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The invention includes compositions and methods based on modulating angiotensin activity to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: November 30, 2010Publication date: November 3, 2011Applicant: BrainCells Inc.Inventors: Carrolee BARLOW, Todd A. Carter, Kai Treuner, Kym I. Lorrain, Corey R. Seehus
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Patent number: 7998971Abstract: The instant disclosure describes compositions and methods for treating diseases and conditions of the central and peripheral nervous system. The disclosure includes compositions and methods based on use of a 4-acylaminopyridine derivative in combination with one or more other neurogenic agents. One 4-acylaminopyridine derivative is MKC-231.Type: GrantFiled: June 21, 2007Date of Patent: August 16, 2011Assignee: BrainCells Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Patent number: 7985756Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a PDE agent, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: GrantFiled: October 20, 2006Date of Patent: July 26, 2011Assignee: BrainCells Inc.Inventors: Carrolee Barlow, Todd A. Carter, Kym I. Lorrain, Jammieson C. Pires, Kai Treuner
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Publication number: 20110092464Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The invention includes compositions and methods based on modulating angiotensin activity to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: December 20, 2010Publication date: April 21, 2011Applicant: BrainCells Inc.Inventors: Carolee BARLOW, Todd A. Carter, Kai Treuner, Kym I. Lorrain
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Publication number: 20110046090Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a GABA agent or GABA analog, in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: August 20, 2010Publication date: February 24, 2011Applicant: BrainCells Inc.Inventors: Carrolee BARLOW, Todd Carter, Andrew Morse, Kai Treuner, Kym Lorrain, Jammieson Pires
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Patent number: 7858611Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The invention includes compositions and methods based on modulation angiotensin activity to stimulate or activate the formation of new nerve cells.Type: GrantFiled: May 9, 2007Date of Patent: December 28, 2010Assignee: BrainCells Inc.Inventors: Carrolee Barlow, Todd A. Carter, Kai Treuner, Kym I. Lorrain
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Publication number: 20100216734Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use nootropic agents, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: November 19, 2009Publication date: August 26, 2010Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain, Dana Gitnick, Jammieson C. Pires
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Publication number: 20100216805Abstract: The disclosure provides compositions and methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure provides compositions and methods based on the use of D-cycloserine in combination with the neurogenic agent, which synergistically stimulates or activates the formation of new nerve cells.Type: ApplicationFiled: February 24, 2010Publication date: August 26, 2010Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym Lorrain
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Publication number: 20100184806Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system including by stimulating or increasing neurogenesis, neuroproliferation, and/or neurodifferentiation. The disclosure includes compositions and methods based on use of a peroxisome proliferator-activated receptor (PPAR) agent, optionally in combination with one or more neurogenic agents, to stimulate or increase a neurogenic response and/or to treat a nervous system disease or disorder.Type: ApplicationFiled: January 20, 2010Publication date: July 22, 2010Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd Carter, Andrew Morse, Kai Treuner, Kym Lorrain
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Publication number: 20100120842Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on muscarinic receptor modulation, such as via inhibition of acetylcholine esterase (AChE) activity, alone or in combination with another neurogenic agent to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: January 22, 2010Publication date: May 13, 2010Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Kym I. Lorrain, Jammieson C. Pires, Andrew Morse, Dana Gitnick, Kai Treuner, Alex Broadhead
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Patent number: 7678808Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a 5HTR agent, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: GrantFiled: May 8, 2007Date of Patent: March 16, 2010Assignee: BrainCells, Inc.Inventors: Carrolee Barlow, Todd Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Patent number: 7678363Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on muscarinic receptor modulation, such as via inhibition of acetylcholine esterase (AChE) activity, alone or in combination with another neurogenic agent to stimulate or activate the formation of new nerve cells.Type: GrantFiled: August 25, 2006Date of Patent: March 16, 2010Assignee: BrainCells IncInventors: Carrolee Barlow, Todd A. Carter, Kym I. Lorrain, Jammieson C. Pires, Andrew Morse, Dana Gitnick, Kai Treuner, Alex Broadhead
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Publication number: 20100009983Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a 5HTR agent, in combination with one or more other neurogenic agents, or anti-astrogenic agent, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: June 25, 2009Publication date: January 14, 2010Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Publication number: 20090325949Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a 5HTR agent, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: June 25, 2009Publication date: December 31, 2009Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Publication number: 20090239834Abstract: The disclosure provides methods and a composition for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis by use of (5-acetamido-N-(5alpha-cholestan-3alpha-yl)-3,5-dideoxy-2-O-methyl-D-glycero-alpha-D-galacto-non-2-ulopyranosonamide(MCC-257).Type: ApplicationFiled: March 23, 2009Publication date: September 24, 2009Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Publication number: 20090197823Abstract: The disclosure provides compositions and methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis by use of a renin inhibitor in combination with one or more neurogenic agents. The disclosure also includes compositions and methods for stimulating or activating the formation of new nerve cells based on the application of a renin inhibitor in combination with one or more neurogenic agents.Type: ApplicationFiled: March 23, 2009Publication date: August 6, 2009Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Publication number: 20080188457Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of one or more biguanides in combination with one or more GSK3-? agents, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: February 1, 2008Publication date: August 7, 2008Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Publication number: 20080171750Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of modafinil, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: January 10, 2008Publication date: July 17, 2008Applicant: BrainCells, Inc.Inventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain
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Publication number: 20080167363Abstract: The present disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of melatonin or other melatoninergic agent, optionally in combination with one or more other neurogenic agents, to stimulate or activate the formation of new nerve cells.Type: ApplicationFiled: December 27, 2007Publication date: July 10, 2008Applicant: BrainCells, IncInventors: Carrolee Barlow, Todd A. Carter, Andrew Morse, Kai Treuner, Kym I. Lorrain, Jeff Redwine, Christine Hoffmaster