Abstract: The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on muscarinic receptor modulation, such as via inhibition of acetylcholine esterase (AChE) activity, alone or in combination with another neurogenic agent to stimulate or activate the formation of new nerve cells.
Type:
Grant
Filed:
August 25, 2006
Date of Patent:
March 16, 2010
Assignee:
BrainCells Inc
Inventors:
Carrolee Barlow, Todd A. Carter, Kym I. Lorrain, Jammieson C. Pires, Andrew Morse, Dana Gitnick, Kai Treuner, Alex Broadhead