Abstract: A silk peptide having neuroprotective and neurofunctional activities and its preparation method are discussed. One method relates to preparing silk protein preferably having neuroprotective activity with weight average molecular weight of 200-100,000 by hydrolysis of silk fibroin; also discussed are a composition for preventing or treating brain disease comprising silk peptide and pharmaceutically acceptable carrier, and a composition for improving brain function.

Abstract: A method for preventing or treating a brain nervous disease includes administering to a subject in need thereof a therapeutically effective amount of a carbon nanotube, wherein the nervous disease is a brain disease or a traumatic central nervous system injury. The composition of the present invention enables patients to recover from physical damage to the brain, exhibits superior efficacy for inhibiting the onset of Parkinson's disease and strokes in animal models for Parkinson's disease and strokes, and the cytotoxic effects of beta amyloid in beta amyloid toxicity tests. Therefore, the composition of the present invention can be effectively used in the preparation of medicine for protecting cranial nerves, therapeutic agents for preventing or treating brain disease, or therapeutic agents for treating traumatic injuries to the central nervous system.

Abstract: A silk peptide having neuroprotective and neurofunctional activities and its preparation method are discussed. One method relates to preparing silk protein preferably having neuroprotective activity with weight average molecular weight of 200-100,000 by hydrolysis of silk fibroin; also discussed are a composition for preventing or treating brain disease comprising silk peptide and pharmaceutically acceptable carrier, and a composition for improving brain function.

Abstract: The present invention relates to a silk protein-mimicking peptide represented by the following Formula 1, a composition for preventing or treating a brain disease, a composition for improving a brain or cognitive function and a composition for preventing or treating diseases, disorders or conditions associated with oxidative stress comprising the peptide: Gly-Xaa1-Gly-Xaa2 ??(1) wherein Xaa1 is Ala, Val, Ser, Tyr, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg; Xaa2 is Ala, Tyr, Val, Ser, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg; or Xaa2 represents Ala, Tyr, Val, Ser, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg residue linked to Gly-Xaa3; and Xaa3 is Tyr, Val, Ala, Ser, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg.

Abstract: The present invention relates to a scaffold for transplanting a stem cell comprising a carbon nanotube without cytotoxicity, and a composition for stem cell therapy comprising (a) a stem cell; and (b) a carbon nanotube serving as a stem cell scaffold without cytotoxicity. The scaffold for transplanting stem cells comprising carbon nanotubes show excellent effects without cytotoxicity on networking between differentiated stem cells and tissues present in transplantation sites, thereby showing significant cell therapy efficacy.