Abstract: In part, the disclosure relates to an analysis system in communication with one or more sources of brain region or brain tissue-specific spectroscopy data; and computer-executable logic, encoded in memory of the analysis system, for interpreting brain region or brain tissue-specific spectroscopy data, where the computer-executable logic is configured for execution of: processing the brain region or brain tissue-specific spectroscopy data to obtain one or more spectroscopic graphical representations of the brain region or brain tissue-specific spectroscopy data; co-registering such representations with regions of interest in imaging data obtained relative thereto, where the imaging data is obtained simultaneously with the spectroscopy data; and displaying a first visual representation of co-registered brain region or brain tissue-specific spectroscopy data and imaging data.