Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
Type:
Grant
Filed:
July 27, 2018
Date of Patent:
November 30, 2021
Assignees:
Ramot at Tel-Aviv University Ltd., BrainStorm Ceil Therapeutics Ltd.