Patents Assigned to Brainsway, Ltd.
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Patent number: 11400289Abstract: Apparatus and methods are described for use with electrophysiological signal detecting electrodes, and a transcranial magnetic stimulation device. A computer processor drives the transcranial stimulation device to apply one or more pulses of transcranial magnetic stimulation to a subject. Within a given time period of applying one of the one or more pulses of transcranial magnetic stimulation to the subject, the computer processor detects an electrophysiological signal of the subject, using the electrophysiological signal detecting electrodes. At least partially in response thereto, the computer processor predicts an outcome of treating the subject for a neuropsychiatric condition, using a given therapy, and generates an output on an output device in response to the predicted outcome. Other applications are also described.Type: GrantFiled: October 25, 2017Date of Patent: August 2, 2022Assignees: BRAINSWAY LTD., ELMINDA LTD., B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD.Inventors: Uri Alyagon, Abraham Zangen, Gaby S. Pell, Yiftach Roth, Ronen Segal, Amir Geva, Ziv Peremen, Boaz Sadeh, Revital Shani-Hershkovich, Dror Haor
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Patent number: 11241584Abstract: Transcranial magnetic stimulation (TMS) is used to modulate permeability of the blood brain barrier in a transient, safe and non-invasive manner. A conventional or deep TMS coil may be placed on a head in a vicinity of a tumor, for example. A series of magnetic pulses is provided to the brain with a tailored stimulation protocol. In one of many possible clinical applications, a pharmaceutical substance may be introduced during a time frame before, during or after providing the magnetic pulses to treat a tumor in the brain.Type: GrantFiled: July 2, 2019Date of Patent: February 8, 2022Assignee: BRAINSWAY, LTD.Inventors: Gaby Pell, Abraham Zangen, Yiftach Roth, Alon Friedman, Udi Vazana
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Patent number: 11207540Abstract: An electromagnetic coil assembly for inducing electromagnetic fields in a head region of a treated subject, the assembly comprising windings configured to define an applicatory coil portion configured for placement in close proximity to the head to induce the electromagnetic fields, and an elevated coil portion passing relatively remote from the head and configured such that electromagnetic fields thereby produced are generated substantially remote from the head, thereby allowing directing the electromagnetic fields generated by the applicatory coil portion substantially accurately to desired inner regions of the head. A support structure is used to enclose and immobilize at least a portion of the windings, while enabling elastic movement of other portions of the windings that are not held by the support structure, to thereby enable size adjustment of the coil to fit over a region of a head of the treated subject.Type: GrantFiled: February 5, 2019Date of Patent: December 28, 2021Assignee: BRAINSWAY LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 10625091Abstract: A transcranial magnetic stimulation coil which is location-specific for medial brain regions or lateral brain regions is designed with multiple spaced apart stimulating elements having current flow in a first direction, and multiple return elements having current flow in a second direction which is opposite the first direction. The multiple stimulating elements are distributed around a central axis of the coil.Type: GrantFiled: October 30, 2017Date of Patent: April 21, 2020Assignee: BRAINSWAY, LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 10589118Abstract: Methods of stimulating a target deep brain region using multiple Transcranial Magnetic Stimulation (TMS) electromagnets positioned over a predetermined cortical regions each having a first-order connection to a target deep brain region and applying TMS so that the applied TMS induces spatial summation and thereby modulation of the target deep brain region.Type: GrantFiled: January 18, 2018Date of Patent: March 17, 2020Assignees: BRAINSWAY LTD., THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRSInventor: M. Bret Schneider
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Publication number: 20190247654Abstract: Apparatus and methods are described for use with electrophysiological signal detecting electrodes, and a transcranial magnetic stimulation device. A computer processor drives the transcranial stimulation device to apply one or more pulses of transcranial magnetic stimulation to a subject. Within a given time period of applying one of the one or more pulses of transcranial magnetic stimulation to the subject, the computer processor detects an electrophysiological signal of the subject, using the electrophysiological signal detecting electrodes. At least partially in response thereto, the computer processor predicts an outcome of treating the subject for a neuropsychiatric condition, using a given therapy, and generates an output on an output device in response to the predicted outcome. Other applications are also described.Type: ApplicationFiled: October 25, 2017Publication date: August 15, 2019Applicants: BRAINSWAY LTD, ELMINDA LTD., BGN TECHNOLOGIES LTD.Inventors: Uri ALYAGON, Abraham ZANGEN, Gaby S. PELL, Yiftach ROTH, Ronen SEGAL, Amir GEVA, Ziv PEREMEN, Boaz SADEH, Revital SHANI-HERSHKOVICH, Dror HAOR
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Patent number: 10335606Abstract: Transcranial magnetic stimulation (TMS) is used to modulate permeability of the blood brain barrier in a transient, safe and non-invasive manner. A conventional or deep TMS coil may be placed on a head in a vicinity of a tumor, for example. A series of magnetic pulses is provided to the brain with a tailored stimulation protocol. In one of many possible clinical applications, a pharmaceutical substance may be introduced during a time frame before, during or after providing the magnetic pulses to treat a tumor in the brain.Type: GrantFiled: April 27, 2017Date of Patent: July 2, 2019Assignee: BRAINSWAY, LTD.Inventors: Gaby Pell, Abraham Zangen, Yiftach Roth, Alon Friedman, Udi Vazana
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Patent number: 10029113Abstract: A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure.Type: GrantFiled: September 10, 2015Date of Patent: July 24, 2018Assignees: BRAINSWAY, LTD., YEDA RESEARCH & DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICESInventors: Abraham Zangen, Yiftach Roth, Pedro C. Miranda, David Hazani, Mark Hallett
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Patent number: 9808642Abstract: A transcranial magnetic stimulation coil which is location-specific for frontal lobe regions, occipital lobe regions, parietal lobe regions, right temporal regions and left temporal regions is designed with multiple spaced apart stimulating elements having current flow in a substantially circular direction, and multiple return elements having current flow in substantially the same circular direction.Type: GrantFiled: February 1, 2016Date of Patent: November 7, 2017Assignee: BRAINSWAY, LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 9802058Abstract: A transcranial magnetic stimulation coil which is location-specific for medial brain regions or lateral brain regions is designed with multiple spaced apart stimulating elements having current flow in a first direction, and multiple return elements having current flow in a second direction which is opposite the first direction. The multiple stimulating elements are distributed around a central axis of the coil.Type: GrantFiled: February 8, 2016Date of Patent: October 31, 2017Assignee: BRAINSWAY, LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 9636517Abstract: Transcranial magnetic stimulation (TMS) is used to modulate permeability of the blood brain barrier in a transient, safe and non-invasive manner. A conventional or deep TMS coil may be placed on a head in a vicinity of a tumor, for example. A series of magnetic pulses is provided to the brain with a tailored stimulation protocol. In one of many possible clinical applications, a pharmaceutical substance may be introduced during a time frame before, during or after providing the magnetic pulses to treat a tumor in the brain.Type: GrantFiled: February 13, 2013Date of Patent: May 2, 2017Assignee: Brainsway, Ltd.Inventors: Gaby Pell, Abraham Zangen, Yiftach Roth, Alon Friedman, Udi Vazana
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Patent number: 9533168Abstract: A coil for transcranial magnetic stimulation which is location-specific for unilateral brain regions is designed with multiple spaced apart stimulating elements having current flow in a first direction, and multiple return elements having current flow in a second direction which is opposite the first direction. The multiple stimulating elements and return elements are distributed on one side of a central axis of the coil.Type: GrantFiled: February 21, 2013Date of Patent: January 3, 2017Assignee: BRAINSWAY, LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 9254394Abstract: A transcranial magnetic stimulation coil which is location-specific for medial brain regions or lateral brain regions is designed with multiple spaced apart stimulating elements having current flow in a first direction, and multiple return elements having current flow in a second direction which is opposite the first direction. The multiple stimulating elements are distributed around a central axis of the coil.Type: GrantFiled: February 21, 2013Date of Patent: February 9, 2016Assignee: BRAINSWAY, LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 9248308Abstract: A transcranial magnetic stimulation coil which is location-specific for frontal lobe regions, occipital lobe regions, parietal lobe regions, right temporal regions and left temporal regions is designed with multiple spaced apart stimulating elements having current flow in a substantially circular direction, and multiple return elements having current flow in substantially the same circular direction.Type: GrantFiled: February 21, 2013Date of Patent: February 2, 2016Assignee: BRAINSWAY, LTD.Inventors: Abraham Zangen, Yiftach Roth
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Patent number: 9132278Abstract: A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure.Type: GrantFiled: March 12, 2014Date of Patent: September 15, 2015Assignees: BRAINSWAY, LTD., YEDA RESEARCH & DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICESInventors: Abraham Zangen, Yiftach Roth, Pedro C. Miranda, David Hazani, Mark Hallett
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Publication number: 20140249352Abstract: A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure.Type: ApplicationFiled: March 12, 2014Publication date: September 4, 2014Applicants: BRAINSWAY, LTD., Yeda Research & Development Co. Ltd. at the Weizmann Institute of Science, Government of the United States of America, As Represented by the Secretary,Inventors: ABRAHAM ZANGEN, YIFTACH ROTH, PEDRO C. MIRANDA, DAVID HAZANI, MARK HALLETT
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Patent number: 8771163Abstract: A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure.Type: GrantFiled: March 4, 2013Date of Patent: July 8, 2014Assignees: Brainsway, Ltd., Yeda Research & Development Co. Ltd. at the Weizmann Institute of Science, The United States of America as Represented by the Secretary, Department of Health and Human ServicesInventors: Abraham Zangen, Yiftach Roth, Pedro C. Miranda, David Hazani, Mark Hallett