Patents Assigned to Brantford Chemicals Inc.
  • Sodium enalapril complex and the use thereof to make sodium enalapril
    Patent number: 5686627
    Abstract: A process for making pure sodium enalapril is provided which includes the step of decomplexing essentially pure sodium enalapril-sodium iodide complex to yield essentially pure sodium enalapril.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: November 11, 1997
    Assignee: Brantford Chemicals Inc.
    Inventors: K. S. Keshava Murthy, Andrew Burchat, Gamini Weeratunga
  • Methods of making ureas and guanidines, including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin, and bunazosin (exemplary of 2- substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor
    Patent number: 5675006
    Abstract: Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: October 7, 1997
    Assignee: Brantford Chemicals Inc.
    Inventors: Khashayar Karimian, Keshava Murthy, Darren Hall
  • Process for the production of an improved form of form 1 ranitidine
    Patent number: 5670671
    Abstract: Process for the production of an improved form of Form 1 Ranitidine Hydrochloride having improved filtration and drying characteristics, said process comprising in a substantially anhydrous hydroxylic solvent, comprising at least one alkanol solvent having 3-4 carbon atoms, adding anhydrous hydrogen chloride gas to Ranitidine free base wherein said substantially anhydrous hydroxylic solvent has the characteristics that it solubilizes the Ranitidine free base and hydrogen chloride gas, and subsequently recovering the improved form of Form 1 Ranitidine Hydrochloride.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: September 23, 1997
    Assignee: Brantford Chemicals Inc.
    Inventor: Keshava Murthy
  • Sodium enalapril complex and the use thereof to make sodium enalapril
    Patent number: 5637730
    Abstract: A process for making pure sodium enalapril is provided which includes the step of decomplexing essentially pure sodium enalapril-sodium iodide complex to yield essentially pure sodium enalapril.
    Type: Grant
    Filed: August 19, 1996
    Date of Patent: June 10, 1997
    Assignee: Brantford Chemicals Inc.
    Inventors: K. S. Keshava Murthy, Andrew Burchat, Gamini Weeratunga