Abstract: Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.
Type:
Grant
Filed:
September 29, 1997
Date of Patent:
June 27, 2000
Assignee:
Brantford Chemicalss Inc.
Inventors:
Khashayar Karimian, Keshava Murthy, Darren Hall