Patents Assigned to Breast Cancer Now
  • TREATMENT RESPONSE PREDICTIVE METHOD
    Publication number: 20240052420
    Abstract: The present invention provides a method for predicting whether a human subject having breast cancer will be resistant to, or sensitive to, therapy with a cyclin-dependent kinase (CDK) inhibitor, the method comprising: a) measuring the gene expression in a sample obtained from the breast tumour of the patient to obtain a sample gene expression profile of at least the following modules: (i) a luminal vs.
    Type: Application
    Filed: September 24, 2021
    Publication date: February 15, 2024
    Applicants: The Institute of Cancer Research: Royal Cancer Hospital, Cancer Research Technology Limited, Breast Cancer Now
    Inventors: Mitchell Dowsett, Eugene Francis Schuster, Chon U Maggie Cheang
  • Methods and medical uses
    Patent number: 11207321
    Abstract: The invention described herein provides a method for the treatment of an oestrogen receptor positive breast cancer in a subject in need thereof comprising administering to said subject a therapeutically effective amount of a compound capable of inhibiting MPS1, wherein: (i) said subject has previously been treated with a CDK4/6 inhibitor; and/or (ii) said breast cancer is resistant to treatment with a CDK4/6 inhibitor.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: December 28, 2021
    Assignees: The Institute of Cancer Research: Royal Cancer Hospital, Breast Cancer Now
    Inventors: Lesley-Ann Martin, Joanna Nikitorwicz-Buniak