Patents Assigned to Brien Holden Vision Institute
  • Publication number: 20140132933
    Abstract: Sets, kits or stocks of anti-myopia contact or spectacle lenses, along with methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Extensive surveys have shown that lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than ?6D central refractive error. In one example, a kit or set of lenses (50, FIG. 15) can have multiple parts or sub-sets (52, 54) each comprising a compartmented container (56a, 56b) with lenses (58a, 58b) arranged according to increments of central corrective power (59a, 59b). The lenses (58a) of the first part (52) have four steps (60a, 61a, 62a, 64a) of peripheral power or defocus to provide therapeutic effect and, while the lenses (58b) of the second part (54) also have four steps (60b, 61b, 62b, 64b), the level of therapeutic effect is higher.
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Applicants: Brien Holden Vision Institute, Novartis AG
    Inventors: Aldo Abraham Martinez, Arthur Ho, Padmaja Rajagopal Sankaridurg, Percy Fabian Lazon, Brien Anthony Holden, Rick Payor, Gregor F. Schmid
  • Patent number: 8672473
    Abstract: Sets, kits or stocks of anti-myopia contact or spectacle lenses, along with methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Extensive surveys have shown that lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than ?6 D central refractive error. In one example, a kit or set of lenses (50, FIG. 15) can have multiple parts or sub-sets (52, 54) each comprising a compartmented container (56a, 56b) with lenses (58a, 58b) arranged according to increments of central corrective power (59a, 59b). The lenses (58a) of the first part (52) have four steps (60a, 61a, 62a, 64a) of peripheral power or defocus to pro vide therapeutic effect and, while the lenses (58b) of the second part (54) also have four steps (60b, 61b, 62b, 64b), the level of therapeutic effect is higher.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: March 18, 2014
    Assignees: Novartis AG, Brien Holden Vision Institute
    Inventors: Aldo Abraham Martinez, Arthur Ho, Padmaja Rajagopal Sankaridurg, Percy Fabian Lazon, Brien Anthony Holden, Rick Payor, Gregor F. Schmid
  • Publication number: 20130101575
    Abstract: The present invention relates to pharmaceutical compositions containing lactoferrin, or fragments of it, and their use in the treatment of wounds, particularly corneal wounds. The present invention also provides a pharmaceutical composition comprising an effective amount of a polypeptide or peptidomimetic consisting essentially of the C-lobe of lactoferrin, or functionally active fragments or variants thereof.
    Type: Application
    Filed: July 1, 2011
    Publication date: April 25, 2013
    Applicant: Brien Holden Vision Institute
    Inventors: Benjamin David Ashby, Qian Garrett, Mark Willcox
  • Publication number: 20130102679
    Abstract: The invention provides a use of panthenol or dexpanthenol in the prevention and/or treatment of contact lens papillary conjunctivitis in a subject. A contact lens care solution containing 0.001 to 10% by dry weight dexpanthenol is also provided.
    Type: Application
    Filed: July 1, 2011
    Publication date: April 25, 2013
    Applicant: BRIEN HOLDEN VISION INSTITUTE
    Inventor: Brien Anthony Holden
  • Publication number: 20130005819
    Abstract: This invention relates to ophthalmic disinfecting and preserving compositions. More particularly, this invention relates to multi-purpose disinfecting solutions [MPDS] suitable for use in or with storage cases for treating multiple-use contact lenses and/or for preserving, disinfecting or packaging of contact and other ophthalmic lenses.
    Type: Application
    Filed: September 10, 2010
    Publication date: January 3, 2013
    Applicant: Brien Holden Vision Institute
    Inventors: Bandarage Mahesh K Bandara, Mark D.P. Wilcox, Hua Zhu
  • Publication number: 20120016027
    Abstract: The present invention relates to methods of preventing ocular discomfort, improving ocular comfort or ameliorating decrease in ocular comfort during wearing of an ophthalmic device (such as a contact lens), that include the administration of compositions comprising fatty acids, such as omega-3 and/or -6 fatty acids. The present invention also relates to fatty acid compositions suitable for use in the methods of the present invention.
    Type: Application
    Filed: July 15, 2011
    Publication date: January 19, 2012
    Applicant: BRIEN HOLDEN VISION INSTITUTE
    Inventor: Mark Willcox
  • Patent number: 8057034
    Abstract: Methods and apparatuses are disclosed for improving peripheral vision by positioning the peripheral image points at a pre-determined and precise position relative to the retina to achieve optimal performance according to one or more pre-selected criteria parameters for optimal peripheral vision performance.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: November 15, 2011
    Assignee: Brien Holden Vision Institute
    Inventors: Arthur Ho, Andrew Robert Whatham, Brien Anthony Holden, Padmaja Rajagopal Sankaridurg, Aldo Abraham Martinez, Earl Leo Smith, III
  • Patent number: 7997727
    Abstract: A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing optical devices and methods comprising the repositioning of peripheral off-axis focal points relative to the retina to produce stimulus for influencing the progression of refractive error while simultaneously controlling the position of the central focal point near to the retina to provide clear central vision and simultaneously providing zones of controlled peripheral defocus and other optical aberrations to improve peripheral vision for select directions of gaze.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: August 16, 2011
    Assignee: Brien Holden Vision Institute
    Inventors: Arthur Ho, Earl Leo Smith, III, Padmaja Sankaridurg, Brien Anthony Holden
  • Patent number: 7909465
    Abstract: An instrument and method for characterizing eye-related optical systems, including the live human eye involves scanning an illuminating light beam from a light source and light detector unit from element to element of a beam deflector array of elements arranged laterally across the optical axis of eye. At each successive element the illuminating beam is deflected to form an interrogating beam that is directed into the eye at a peripheral angle that depends upon the lateral location of the deflector element. A return beam is reflected or back-scattered from the cornea and returned via the same deflector element to the light source and detector unit. This allows the interrogating beams to be scanned sufficiently rapidly into the eye to greatly reduce the variation of eye fixation and gaze that accompany other methods of measuring peripheral refraction or aberration of a natural eye.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: March 22, 2011
    Assignee: Brien Holden Vision Institute
    Inventors: Arthur Ho, Brien Anthony Holden, Klaus Ehrmann