Patents Assigned to Brigham Young University
  • Patent number: 11224124
    Abstract: A flexible electronics assembly includes a single-piece substrate having two regions of rigidity separated by a localized region of flexibility. The localized region of flexibility has a lower rigidity than the two regions of rigidity. The two regions of rigidity are angularly deflectable from a planar configuration of the single-piece substrate to a non-planar configuration of the single-piece substrate by hinging action of the localized region of flexibility. At least one electronic component is mounted on at least one of the two regions of rigidity.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: January 11, 2022
    Assignee: Brigham Young University
    Inventors: Bryce Parker DeFigueiredo, Spencer Magleby, Larry Howell
  • Patent number: 11215508
    Abstract: A temperature measuring system is disclosed herein. The temperature measuring system includes an optical assembly and a spectral data receiver. The temperature measuring system views passing gas and measures the radiant response of a selected gas. The measurement includes radiant intensities with respect to wavelengths in the infrared region.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: January 4, 2022
    Assignees: Solar Turbines Incorporated, Brigham Young University
    Inventors: Darrel Zeltner, Dale R. Tree, Mohsen Rezasoltani, Scott Egbert
  • Patent number: 11215428
    Abstract: An example barrier can be switchable between an at least partially collapsed state and at least partially expanded state (e.g., a deployed state). For example, the barrier can be formed from a continuous sheet and a plurality of rigid sections (e.g., rigid panels) attached or incorporated into the continuous sheet. The barrier can also include a plurality of hinges, such as hinge lines, between the panels that are formed from the continuous sheet. The hinges enable the barrier to be rigid foldable (e.g., the hinges can fold and unfold while the rigid sections remain stiff and rigid) between the expanded and collapsed states.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: January 4, 2022
    Assignee: BRIGHAM YOUNG UNIVERSITY
    Inventors: Larry L. Howell, Spencer P. Magleby, David C. Morgan, Terri Bateman, Jeffrey E. Niven, Alex Avila, Erica Crampton, Kyler Tolman, Jacob Greenwood, Peter Schleede
  • Publication number: 20210379091
    Abstract: The present disclosure describes compositions and methods for deactivating coronavirus. A method includes providing a deactivation composition including one or more CSA compounds and a carrier, administering the deactivation composition to a subject, and the deactivation composition deactivating coronavirus virions in the subject or coming into contact with the subject. The method can thereby prevent, decrease, or inhibit a coronavirus infection, such as COVID-19, of the subject.
    Type: Application
    Filed: June 7, 2021
    Publication date: December 9, 2021
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Paul B. Savage, Michael C. Moore
  • Publication number: 20210363174
    Abstract: Cationic steroidal antimicrobial (CSA) compounds having a structure of Formula I, II or III, or salt thereof, wherein at least one of R1-R18, (e.g., R18) includes a terpenyl group attached via an ester or amide linkage and at least one R1-R18, (e.g., R3, R7 and R12) is an amino acid linked to the steroidal backbone by an ester or amide linkage: R18 has the following structure: —R19—(C?O)—X—R20 where R19 is omitted or alkyl, alkenyl, alkynyl, or aryl, X is oxygen or nitrogen, and R20 is a terpenyl group. R3, R7 and R12 have the following structure: R22R23N—R21—(C?O)—X— where R21 is substituted or unsubstituted alkyl, X is oxygen or nitrogen, and R22 and R23 are independently hydrogen, alkyl, alkenyl, alkynyl, or aryl.
    Type: Application
    Filed: May 19, 2021
    Publication date: November 25, 2021
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventor: Paul B. Savage
  • Publication number: 20210361672
    Abstract: The present disclosure describes compositions and methods for preventing and/or treating microbial infections of ciliated tissues, such as tissues of the trachea, lungs, and sinuses. A treatment composition comprises a CSA compound, a poloxamer, and a carrier. The combination of CSA compound and poloxamer allows higher concentrations of CSA compound to be used. Where such doses would normally disrupt ciliary function, the poloxamer prevents damage to ciliated tissue without inhibiting the antimicrobial effectiveness of the CSA compound.
    Type: Application
    Filed: March 7, 2019
    Publication date: November 25, 2021
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Carl Genberg, Paul B. Savage
  • Publication number: 20210355155
    Abstract: Cationic steroidal antimicrobial (CSA) compounds having a structure of Formula I, II or III, or salt thereof, wherein at least one of at least one of R1-R18, (e.g., R3, R7 and R12) is linked to the steroidal backbone by a urethane group: At least one of R1-R18, (e.g., R3, R7 and R12) has the following urethanyl structure: —O—(C?O)—NR19R20 where R19 and R20 are independently hydrogen, alkyl, alkenyl, alkynyl, aryl, aminoalkyl, aminoalkenyl, aminoalkynyl, or aminoaryl, provided that at least one of R19 or R20 includes an amino group (e.g., R19 is hydrogen and R20 is (C2-C6)aminoalkyl). R18 can have the following structure: —R21—(C?O)—NR22R23 where R21 is omitted or alkyl, alkenyl, alkynyl, or aryl, and R22 and R23 are hydrogen, alkyl, alkenyl, alkynyl, or aryl, provided that at least one of R22 or R23 is not hydrogen.
    Type: Application
    Filed: May 12, 2021
    Publication date: November 18, 2021
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventor: Paul B. Savage
  • Publication number: 20210319568
    Abstract: A UAS may use camera-captured ground feature data to iteratively estimate pose change through a Kalman filter. To avoid excessive drift, the UAS may periodically perform a reset by publishing delta pose and covariance as an edge in a global pose graph, by zeroing out the delta pose and covariance. To further improve global pose estimation, two UASs may share range information and associated pose graph information, thereby providing an additional constraint for each UAS to use in its pose graph optimization.
    Type: Application
    Filed: April 12, 2021
    Publication date: October 14, 2021
    Applicant: Brigham Young University
    Inventors: Gary Ellingson, Timothy McLain, Kevin Brink
  • Patent number: 11142843
    Abstract: Embodiments disclosed herein are related to polycrystalline textured materials exhibiting heterogeneous templated grain growth, methods of forming such materials, and related systems. An example of a method of forming a polycrystalline textured material exhibiting heterogeneous templated grain growth includes providing a plurality of seeds. The method also includes aligning at least some of the plurality of seeds (e.g., single-crystal seeds) so that a selected crystallographic orientation of at least some of the plurality of seeds are substantially aligned with each other. Additionally, the method includes positioning the plurality of seeds in a powder matrix. The method then includes pressing the plurality of seeds and the powdered matrix to form a green body. Further, the method includes sintering the green body at a temperature that is sufficient to grow a plurality of grains from corresponding ones of the plurality of seeds to form the polycrystalline textured material.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: October 12, 2021
    Assignee: BRIGHAM YOUNG UNIVERSITY
    Inventors: Oliver Kent Johnson, Dallin James Frandsen
  • Patent number: 11143639
    Abstract: A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides column 50 a liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and providing an attachable module containing a module input port, a column, a heater for the column, and at least one detector for on-column detection, then attaching the module to the LC device using a press-fit connection that enables the sample in the solvent to be pumped through the column to the at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to the LC system for collection and analysis.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: October 12, 2021
    Assignee: BRIGHAM YOUNG UNIVERSITY
    Inventors: Xiaofeng Xie, Luke T. Tolley, Paul B. Farnsworth, H. Dennis Tolley, Milton L. Lee
  • Publication number: 20210310924
    Abstract: Time multiplexing an electromagnetic trap beam may be used to generate trap shapes/geometries to trap one or more particles with one electromagnetic beam by directing the electromagnetic beam at a pattern of different locations with sufficient rapidity to form an effective shape/geometry. Additionally, multiplexing an electromagnetic trap beam may be used to shutter trapping electromagnetic radiation to protect a viewer, use the same beam for multiple functions, move and organize particles, and generate illumination effects.
    Type: Application
    Filed: March 15, 2021
    Publication date: October 7, 2021
    Applicant: Brigham Young University
    Inventors: Daniel Smalley, Braden Huffman, Stephen Griffith
  • Patent number: 11078698
    Abstract: A hinged mechanism includes: panels; and hinges connecting respective pairs of the panels to each other in a closed loop so that the hinged mechanism is non-planar, wherein at least one of the hinges is a rolling-contact hinge. All of the hinges can be rolling-contact hinges. The closed-loop hinged mechanism can comprise at least four hinges, each of the at least four hinges being a sole connection between a respective adjacent pair of the panels. A cross section of rolling surfaces of the rolling-contact hinge can be circular. A cross section of rolling surfaces of the rolling-contact hinge can be non-circular.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: August 3, 2021
    Assignee: Brigham Young University
    Inventors: Robert J. Lang, Larry L. Howell, Spencer P. Magleby, Todd G. Nelson
  • Patent number: 11054390
    Abstract: Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: July 6, 2021
    Assignees: The Regents of the University of California, Brigham Young University
    Inventors: William Dunbar, Holger Schmidt, Aaron Hawkins
  • Publication number: 20210196769
    Abstract: Compositions for affecting the intestinal microbiome of a mammalian subject can include a pharmaceutically-acceptable carrier and greater than or equal to 1×104 PFU/mL or PFU/mg of bacteriophage having a tropism that includes an obesogenic and/or inflammatory bacterium associated with an intestinal microbiome of a mammal. Processes for preparing the disclosed compositions can include isolating the bacteriophage from an environmental source, characterizing the bacteriophage, and combining the bacteriophage with the pharmaceutically acceptable carrier at greater than or equal to 1×104 PFU/mL or PFU/mg. Methods can include administering the disclosed compositions to a mammalian subject with or without co-administration of the disclosed probiotics.
    Type: Application
    Filed: May 23, 2019
    Publication date: July 1, 2021
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Laura Bridgewater, Gongze Zhao
  • Publication number: 20210177004
    Abstract: Hardpack frozen desserts providing a carbonation sensation even after frozen storage over an extended shelf life, and methods of making such hardpack frozen desserts are described. Hardpack frozen desserts have a particular solute content, providing a solute molarity of at least 1.0 molar, and/or a solute molality of at least 0.78 molal, and/or an Aw of the mixture of 0.91 or less.
    Type: Application
    Filed: August 7, 2019
    Publication date: June 17, 2021
    Applicant: Brigham Young University
    Inventors: Michael L. Dunn, Frost M. Steele
  • Patent number: 11013451
    Abstract: A system for monitoring a movement disorder includes a movement detector configured to track at least one point of reference in three dimensions, and a computing device communicatively coupled with the movement detector. The computing device is configured to receive movement data associated with the at least one point of reference over a period of time, perform a kinematic data analysis based on the movement data, compute a weighted score using the kinematic data analysis, compute a trend based on historical movement data, the weighted score and the trend being associated with the movement disorder, and display the weighted score, the trend and the movement data on a display associated with the computing device.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: May 25, 2021
    Assignee: Brigham Young University
    Inventors: Nathan Stanford, Steven Charles
  • Publication number: 20210145764
    Abstract: Described herein are compositions and methods for the prevention and/or treatment of at least one condition or disorder of a) skin and accessory structures of the skin, b) musculoskeletal system, c) cardiovascular system, d) inflammatory system, e) neurological system, f) cancer, and g) endocrine/metabolic system, and/or for improving the health status of a subject. The composition includes one or more polyphenolic compound, its isomer or analog; and one or more other active ingredient selected from the group consisting of collagen, vitamin C, vitamin E, zinc, grape seed extract, niacinamide, hydroxy acids, hyaluronic acid, and coenzyme Q10. The composition may also or alternatively include cannabidiol (CBD).
    Type: Application
    Filed: November 12, 2020
    Publication date: May 20, 2021
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventor: Edwin Douglas LEPHART
  • Publication number: 20210138006
    Abstract: Kits for use in treating or preventing an infection caused by a primary bacterium or for use in reducing or preventing overpopulation of the primary bacterium can include a bystander bacterium having a genomically-encoded bacteriotoxin specific for at least the primary bacterium and a first bacteriophage tropic for the bystander bacterium. The bystander bacterium can be provided as a live culture and infection of the bystander bacterium by the first bacteriophage causes expression of the genomically-encoded bacteriotoxin. Methods of treating or preventing an infection caused by a primary bacterium or for reducing or preventing overpopulation of the primary bacterium can include administering a bacteriophage tropic for a bystander bacterium that has a genomically-encoded bacteriotoxin that is expressed upon infection by the first bacteriophage and is specific for at least the primary bacterium.
    Type: Application
    Filed: July 12, 2019
    Publication date: May 13, 2021
    Applicant: Brigham Young University
    Inventor: Sandra Hope
  • Patent number: 10959433
    Abstract: This disclosure relates to sporicidal compositions and uses thereof. The sporicidal compositions include one or more cationic steroidal antimicrobials (CSAs). The sporicidal compositions may be applied to an object to kill or deactivate bacterial spores contacting the sporicidal composition. The object may be a food product, food processing equipment, industrial equipment, or healthcare facility objects. The sporicidal composition may be administered to a subject that has, is suspected to have, or is at risk for an infection associated with spore-forming bacteria.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: March 30, 2021
    Assignee: BRIGHAM YOUNG UNIVERSITY
    Inventor: Paul B. Savage
  • Patent number: 10921279
    Abstract: In a general aspect, an apparatus can include a substrate and a post disposed on the substrate. The post can include a plurality of nanotubes and extend substantially vertically from the substrate. The post can have an aspect ratio of a height of the post to a diameter of the post of greater than or equal to 25:1.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: February 16, 2021
    Assignee: Brigham Young University
    Inventors: Guohai Chen, Robert C. Davis, Richard Vanfleet