Abstract: The present disclosure integrates an actuated tilting rehabilitation table, video tracking of the patient arm and opposite shoulder, a low-friction forearm support with grasping force sensing, remote data transmission and additional weighing means, one or more large displays, a computer and a plurality of simulation exercises, such as video games. The patient can be monitored by a local or remote clinician. The table tilts in order to increase exercise difficulty due to gravity loading on the patient's arm and shoulder. In one embodiment, the actuated tilting table tilts in four degrees of freedom.

Abstract: Systems and methods for providing cognitive therapy to a patient are provided, which include a head mounted device wearable by the patient, a display configured to present one or more cognitive game scenes to the patient, one or more controllers for interacting with the cognitive training scenes, a cognitive engagement detection device configured to detect cognitive engagement of the patient and generate data indicative of the cognitive engagement of the patient, and a processor. The processor determines a level of cognitive engagement of the patient based at least in part on the data generated by the cognitive engagement detection device, determines performance of the patient interacting with the one or more cognitive training scenes based on information received from the one or more controllers, and determines cognitive improvement of the patient based on the cognitive engagement, cognitive medication taken, and the performance of the patient.

Abstract: A system provides bi-manual game-based integrative therapy combining cognitive training with mild upper body physical exercising during game play. The system includes a pair of interfaces tracking a user's arms in 3D and detect trigger pressing. Custom therapeutic game controllers that detect grasping force, finger extension, 3D hand position, skin temperature and pulse may be used. Using one of these interfaces the patient plays a series of custom games displayed on a laptop, medical grade workstation, or other computer platform. The whole therapeutic system may be integrated on a medical cart, so to make the system mobile and easier to place in a clinical setting. Games were designed to improve motor control, shoulder strength, finger and arm range of motion, task sequencing, focusing, decision making (executive function), short term and long term visual/auditory memory, and were progressed in difficulty over 6 to 8 weeks of therapy. This therapy reduces depression.

Abstract: The majority of cognitive virtual reality (VR) applications have been for therapy, and not cognitive screening/scoring. Provided herein is the BrightScreener™ and its first pilot feasibility study for evaluating elderly with various degrees of cognitive impairment. BrightScreener is a portable (laptop-based) serious-gaming system which incorporates a bimanual game interface for more ecological 3D interaction with virtual worlds. A pilot study determined that BrightScreener is able to differentiate levels of cognitive impairment based solely on game performance, as well as to evaluate the technology acceptance by the target population. Subsequent group analysis of the Pearson correlation coefficient showed a high degree of correlation between the subjects' MMSE scores and their Composite Game Scores (0.90, |P|<0.01). Despite the small sample size (n=11), results suggest that serious-gaming strategies can be used as a digital technique to stratify levels of Cognitive Impairment.

Abstract: The majority of cognitive virtual reality (VR) applications have been for therapy, and not cognitive screening/scoring. Provided herein is the BrightScreener™ and its first pilot feasibility study for evaluating elderly with various degrees of cognitive impairment. BrightScreener is a portable (laptop-based) serious-gaming system which incorporates a bimanual game interface for more ecological 3D interaction with virtual worlds. A pilot study determined that BrightScreener is able to differentiate levels of cognitive impairment based solely on game performance, as well as to evaluate the technology acceptance by the target population. Subsequent group analysis of the Pearson correlation coefficient showed a high degree of correlation between the subjects' MMSE scores and their Composite Game Scores (0.90, |P|<0.01). Despite the small sample size (n=11), results suggest that serious-gaming strategies can be used as a digital technique to stratify levels of Cognitive Impairment.