Abstract: A device suitable for dispensing a liquid substance, such as an ophthalmological substance, including a container; a dispenser for dispensing the substance and which includes a piston element, loaded by the pressure of the pressurized substance so as to adopt a standby position by default that prevents the preloading chamber from being flooded by a dose of the substance; and a valve element capable of enabling a connection between the preloading chamber and the outside. The device has an actuation mechanism that sequentially compresses a volume of air used for moving the piston element from the standby position thereof, allowing a dose of the substance to flood the preloading chamber to subsequently mechanically actuate the valve element and simultaneously enable the connection to the outside of the preloading chamber as well as of the volume of air previously used for moving the piston element from the standby position thereof.

Abstract: A device suitable for dispensing a liquid substance, such as an ophthalmological substance, including a container; a dispenser for dispensing the substance and which includes a piston element, loaded by the pressure of the pressurized substance so as to adopt a standby position by default that prevents the preloading chamber from being flooded by a dose of the substance; and a valve element capable of enabling a connection between the preloading chamber and the outside. The device has an actuation mechanism that sequentially compresses a volume of air used for moving the piston element from the standby position thereof, allowing a dose of the substance to flood the preloading chamber to subsequently mechanically actuate the valve element and simultaneously enable the connection to the outside of the preloading chamber as well as of the volume of air previously used for moving the piston element from the standby position thereof.

Abstract: The invention relates to a handheld aesthesiometer, comprising a gas lung connected with intermediation from first valve means to a source of gas and comprising an expandable cavity intended to house a volume of gas in a loading phase of the aesthesiometer; an outlet nozzle connected to the gas lung with intermediation from second valve means and suitable for directing a puff of the volume of the gas housed in the gas lung in a firing phase of the aesthesiometer; and a mechanism to ensure in the aforementioned firing phase of the aesthesiometer the release of the puff of the volume of gas contained in the gas lung in the direction of the outlet nozzle by means of a controlled contraction of the expandable cavity of the gas lung in order to ensure a substantially constant outlet pressure.