Patents Assigned to Bristol Myers Squibb Comp.
  • Methods for the preparation of taxanes using oxazolidine intermediates
    Patent number: 6365750
    Abstract: Novel oxazolidines finding utility as intermediates in the preparation of C-13 acyloxy sidechain-bearing taxanes such as paclitaxel and analogs thereof. The present invention also relates to novel methods of coupling the oxazolidines to form the aforementioned taxanes, and to methods of preparing the oxazolidines.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: April 2, 2002
    Assignee: Bristol Myers Squibb Comp.
    Inventors: John K. Thottathil, Ivan D. Trifunovich