Abstract: The present application describes novel lactams and derivatives thereof of formula I:
or pharmaceutically acceptable salt forms thereof, wherein ring B is a 4-8 membered cyclic amide comprising 0-3 additional heteroatoms selected from N, O, and S, which are useful as metalloprotease inhibitors.
Type:
Grant
Filed:
July 10, 2001
Date of Patent:
September 16, 2003
Assignee:
Bristol-Myers Squibb Pharme Company
Inventors:
Thomas P Maduskuie, Jingwu Duan, Stephen E Mercer