Abstract: Compound of formula (I) ##STR1## wherein Ar represents an optionally substituted phenyl or heteroaryl group, m is 1 or 2, n is 0, 1, 2, 3 or 4, X represents --COOH or --CONHOH and R.sub.1, R.sub.3 and Y are as defined in the specification,are inhibitors of metalloproteinases involved in tissue degradation.
Type:
Grant
Filed:
September 8, 1997
Date of Patent:
November 24, 1998
Assignee:
Britisch Biotech Pharmaceuticals, Ltd.
Inventors:
Mark Whittaker, Raymond Paul Beckett, Zoe Marie Spavold, Fionna Mitchell Martin