Patents Assigned to British Columbia Caner Agency Branch
  • Mutated HOXB4 proteins with improved stability, and methods of use thereof
    Patent number: 8039436
    Abstract: A polypeptide, the amino acid sequence of which comprises a sequence as set forth in SEQ ID NO:2, including at least one mutation within the degron domain of the polypeptide encompassed between positions 1 and 35 of the sequence, wherein said at least one mutation reduces the susceptibility of the polypeptide to ubiquitin-proteasome degradation.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: October 18, 2011
    Assignees: British Columbia Caner Agency Branch, Adaerata, Limited Partnership, Valorisation-Recherche, Limited Partnership, RSEM, Limited Partnership
    Inventors: Guy Sauvageau, Keith Humphries, Denis-Claude Roy, Nathalie Beslu