Abstract: The invention relates to recombinant cell lines, in particular mamalian cell lines, capable of expressing recombinant CDw52 antigen or an antigenic fragment thereof. The cell lines can be used for the production of recombinant CDw52 antigen and in assaying for anti-CDw52 antibody in a sample.

Abstract: A hydrodynamic fluid film bearing in which a plurality of circumferentially spaced bearing elements are provided, defining areas of support for the rotating part of the bearing. At least some of the bearing elements are adjustable during operation to vary lubrication conditions in the fluid film. The bearing elements are of sufficiently high stiffness that the position of the entire bearing surface of each element is essentially independent of the pressure in the fluid film encountered during operation.The bearing allows complete control of the lubrication conditions and can be adjusted for optimum performance over a wide range of speed and load.

Abstract: A micromechanical sensor has a plurality of sensing elements (14a-14d) which are supported at respective support regions (12a-12d). A first set of the sensing elements defines the sensing gap. In one arrangement this is defined by sensing elements supported by adjacent support regions. In another embodiment the sensing gap is defined between one sensing element and a reference beam formed by connection of the return legs of two diametrically opposed sensing elements. The sensing elements are substantially similar one to another and each sensing element comprises an outgoing elongate leg extending away from its associated support region and a return leg substantially parallel to the outgoing leg extending towards the support region. By providing sensing elements which are substantially similar in shape and arranged in this way, the effects of thin film stress are minimized.

Abstract: A pesticidal compound, suitable for combating soil borne insect pests has formula I: ##STR1## in which formula: Ar.sub.A represents a phenyl or naphthyl group optionally substituted by one or more groups selected from halogen, alkoxy, haloalkoxy, methylenedioxy, C.sub.1 -C.sub.6 alkyl and C.sub.1 -C.sub.6 haloalkyl; andAr.sub.B represents a phenoxy, phenyl, benzyl or benzoyl-substituted phenyl group which is optionally further substituted;the configuration of the aryl cyclopropyl group and the group CH.sub.2 Ar.sub.B about the double bond being mutually trans.

Abstract: The invention describes apparatus for, and a method of, active acoustic screening and combined active acoustic and magnetic screening, of magnetic field coils, which pass a time varying current and which reside in relatively high static magnetic fields, typically greater than about 0.1 T. The invention is particularly well suited for acoustic screening of magnetic field gradient coils used in Magnetic Resonance Imaging (MRI). In a preferred embodiment a closed loop carrying current is arranged such that two different parts of the loop are mechanically coupled, dimensioned and arranged with respect to one another such that Lorentz forces experienced by the magnetic equipment are substantially reduced and preferably cancelled.In a different embodiment the invention is modified so as to permit simultaneous magnetic and acoustic screening.

Abstract: Cyclopentaquinazoline of the formula (I): ##STR1## wherein R.sup.1 is hydrogen, amino, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 hydroxyalkyl or C.sub.1-4 fluoroalkyl;wherein R.sup.2 is hydrogen, C.sub.1-4 alkyl, C.sub.3-4 alkenyl, C.sub.3-4 alkynyl, C.sub.2-4 hydroxyalkyl, C.sub.2-4 halogenoalkyl or C.sub.1-4 cyanoalkyl;Ar.sup.1 is phenylene, thiophenediyl, thiazolediyl, pyridinediyl or pyrimidinediyl which may optionally bear one or two substituents selected from halogeno, hydroxy, amino, nitro, cyano, trifluoromethyl, C.sub.1-4 alkyl and C.sub.1-4 alkoxy; andwherein R.sup.3 is a group of the formula:--A.sup.1 --Ar.sup.2 --A.sup.2 --Y.sup.1in which A.sup.1, A.sub.2, Y.sup.1 and Ar.sub.2 are defined in claim 1;or a pharmaceutically acceptable salt or ester there of are of therapeutic value particularly in the treatment of cancer.

Abstract: A method of investigation of a body including applying interrogatory electrical signals at different frequencies to the body. First signals are obtained representing first electrical impedance measurements at the different frequencies. Second signals are obtained representing subsequent second electrical impedance measurements at the different frequencies after a change in the internal state of the body. Characteristics of part of the body are selectively determined in response to the first and second signals at the different frequencies. The invention has application in electrical impedance tomography techniques where the different frequency behavior of different parts of the body associated with temporal changes can be used to improve organ resolution and tissue differentiation.

Abstract: The anthelmintic efficacy in animals and humans of a benzimidazole such as fenbendazole, albendazole, oxfendazole or trichlabendazole is potentiated by use with piperonyl butoxide or other methylenedioxyphenyl synergist.

Abstract: The invention provides an apparatus and method for delivering laser radiation to a substrate (20,120) involving a laser radiation source (1), delivery means (2) to transmit the laser radiation from the source, a delivery head (3) to direct the laser radiation from the delivery means onto the substrate. The delivery head has isolation means to isolate a selected target area from its surroundings by substantially preventing escape of laser radiation, and viewing means are provided to enable an operator to view the selected target area. The apparatus is specifically for application in curing restorative or prophylactic tooth coatings, such as vitreous dental compositions or sol gels.

Abstract: The rate of healing of a wound can be delayed or anomalous wound healing inhibited by applying an Agaricus bisporus lectin (agglutinin) to the site of the wound.

Abstract: An identification system comprises an interrogator and a plurality of transponders. The interrogator includes a transmitter which transmits at least two independent interrogation signals to the transponders, and a receiver for receiving response signals from the transponders. The interrogator also includes processor means for identifying the transponders from data in the received response signals. Each transponder comprises receiving means, a code generator, and transmitter means connected to the code generator. On receipt of at least one of the transmitted interrogation signals the transponder transmits a response signal containing data which identifies it. The interrogation signals may be transmitted continuously or intermittently. In a preferred embodiment, the interrogation signals are relatively narrow bandwidth signals at different frequencies.

Abstract: A method of treating or preventing clinical manifestations associated with diseases caused by infectious organisms which express antigens which in the patient stimulate secretion of harmful levels of at least one cytokine, other than diseases caused by organisms which stimulate secretion of cytokines only by expression of lipopolysaccharide, which method comprises administering to a human in need thereof an effective non-toxic amount of a material selected from the group consisting of inhibitors and immunogens wherein said inhibitors are pharmacologically acceptable materials which, in vitro, reduce or abolish secretion, by at least one of human monocytes and mouse peritoneal macrophages, of tumour necrosis factor following stimulation with a phospholipid-containing; tumour necrosis factor-inducing antigen other than lipopolysaccharide, and wherein said immunogens are pharmacologically acceptable materials comprising at least one B-cell epitope and which stimulate production of antibodies which, in vitro, red

Abstract: The gene which expresses the light (.beta.-)chain of kinesin contains at its 5'-end a region of DNA of high secondary structure which provides a strong enhancer of translation. In the human kinesin gene it forms a double hairpin loop. The secondary structure, optionally with flanking sequence, is claimed as isolated DNA. Constructs in which it serves is an enhancer for expression of foreign DNA are also claimed.

Abstract: A protein which inhibits milk secretion by lactating goats has been isolated from milk by anion exchange of a defined whey fraction, optionally followed by chromatofocussing, and is defined by reference to peaks in which it is found, its molecular weight of 7.6 KDa and pI of 4.8.

Abstract: A highly efficient linear amplifier and/or modulator and demodulator comprising first and second feedback loops is provided. Each loop processes a component of the input signal and the component signals are recombined at, for example, a summing junction 18. The feedback signals for each loop are dependent upon the output signal and are in phase quadrature. The input signal is separated into I and Q signals, which are also in phase quadrature, by a component separator 10.

Abstract: An apparatus for measuring fluid flow velocity includes structure for varying an energy content of a volume of a fluid at a first pre-selected point to the flow path and structure for detecting the variation in the energy content of the fluid at a second pre-selected point in the flow path. The structure for varying the energy content includes structure for injecting a quantity of liquified gas into the fluid thereby to cause variation in the energy content. A method for measuring fluid flow velocity is also disclosed.

Abstract: A method and device for use in assessing the state of blood vessels within the human or animal body is provided. A vessel segment is identified for investigation, and at least one blood pressure responsive device is used to obtain pulse volume recordings of different sites, representing pressure at sites proximal and distal to the vessel segment. From the waveform signals obtained, Fourier transform spectra are determined for the respective sites and the transfer function between them is calculated. This is then analyzed to determine a clinically significant parameter, such as the integral of the transfer function, and this can be compared with a predetermined value to provide an indication as to the state of the vessel segment.

Abstract: An improved process for the production of a pharmaceutical composition comprising p-hydroxyacetanilide and L-cysteine or a compound which is converted thereto in vivo comprises mixing p-hydroxyacetanilide and L-cysteine or its precursor in the solid state and then shaping the solid mixture.

Abstract: A whiteware ceramic composition is provided comprising a filler, 4 to 10% by weight of a flux having a median particle size of below 6 microns, a prefired ceramic material milled separately from the other components, and raw clay constituting from 5 to 20% by weight of the composition. Fired whiteware made by firing the composition of the invention is also disclosed.

Abstract: Compounds of general formula (I) ##STR1## wherein n is 11, 12 or 13 and R is bromine or hydroxy, and physiologically acceptable salts thereof, with the proviso than when n is 11, R is not bromo, have been found to be effective as non-toxic agents against herpesviruses and retroviruses.