Patents Assigned to British Technology Group Ltd.
  • Publication number: 20060165731
    Abstract: Vaccines active against coccidiosis in domestic fowls contain attenuated precocious strains of Eimeria species.
    Type: Application
    Filed: September 13, 2005
    Publication date: July 27, 2006
    Applicant: British Technology Group Ltd.
    Inventors: Vincent McDonald, Martin Shirley
  • Patent number: 5955463
    Abstract: The invention relates to quinazoline derivatives or pharceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them.The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 is (1-4C)alkyl; the quinazoline ring may optionally bear one or two further substituents selected from halogeno, (1-4C)alkyl and (1-4C)alkoxy;R.sup.2 is hydrogen or (1-4C)alkyl;R.sup.3 includes hydrogen and (1-4C)alkyl; andAr is optionally substituted phenylene or heterocyclene;or a pharmaceutically-acceptable salt or ester thereof.
    Type: Grant
    Filed: March 9, 1993
    Date of Patent: September 21, 1999
    Assignees: Zeneca Limited, British Technology Group Ltd.
    Inventors: Stephen John Pegg, James Michael Wardleworth
  • Patent number: 5879399
    Abstract: An endoprosthetic acetabular component of overall cup form is improved by the provision of an outer part (100; 300; 500) for securement to bone and a plurality of inner parts (200; 400; 600) individually selectively interconnectable with the outer part in like manner but providing a dished articulating surface (203; 403; 603) in respectively different predetermined positions varying in depth and/or inclination. The interconnection is preferably rotatably adjustable relative to the cup mouth, suitably by the provision of mutually complementary indented/detented surface formations (104,202; 304,402; 505,607) on the parts. The outer part may also be selectable from a range adapted to respectively different manners of securement to bone.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: March 9, 1999
    Assignee: British Technology Group Ltd.
    Inventor: John Christian Tracey Church
  • Patent number: 5880162
    Abstract: A pesticidal compound of formula I: ##STR1## in which formula: either R.sup.1 is hydrogen and R.sup.2 represents a cyclopropyl group or R.sup.1 and R.sup.2 each represent an alkyl group, which alkyl groups may be the same or different;Ar.sub.A represents an optionally substituted phenyl or naphthyl group;Ar.sub.B represents a phenoxy, phenyl, benzyl or benzoyl-substituted phenyl group which is optionally further substituted;the configuration of the groups Ar.sub.A --CR.sup.1 R.sup.2 and --CH.sub.2 Ar.sub.B about the double bond being mutually trans.Preferably Ar.sub.A is a substituted phenyl group; more preferably being substituted at the 4-(para) position by halogen, alkoxy or haloalkyl.Further provided is a process for the preparation of a pesticidal compound of formula I in which a compound comprising a moiety ##STR2## and a compound comprising a moiety Ar.sub.B -- are reacted together forming a link --CH.dbd.C(F)CH.sub.2 -- between ##STR3## and Ar.sub.B in the compound of formula I.
    Type: Grant
    Filed: October 21, 1996
    Date of Patent: March 9, 1999
    Assignee: British Technology Group, Ltd.
    Inventors: Bhupinder Pall Singh Khambay, Mu-Guang Liu
  • Patent number: 5863763
    Abstract: The present invention relates to novel peptides isolated from the blowfly Calliphora vomitoria. The invention also relates to nucleic acid molecules encoding these peptides, vectors and host cells comprising these nucleic acid molecules, and chemical and biological methods for producing these peptides. The present peptides have novel sequences comprising hydroxyproline residues and C-terminal amide groups which give the peptides improved stability in the gut of insects. The peptides of the invention are related to the allatostatin class of insect neuropeptides, have inhibitory effects on gut motility in the blowfly C. vomitoria, and have allatostatic effects in cockroaches of the species Diploptera punctata and Periplaneta americana. The invention also provides compositions comprising the present peptides which may be used as insecticides, and provides methods of killing or controlling insects comprising administering the nucleic acid molecules, peptides or compositions of the invention to insects.
    Type: Grant
    Filed: September 11, 1996
    Date of Patent: January 26, 1999
    Assignee: British Technology Group Ltd.
    Inventors: Hanne Duve, Alan Thorpe, Anders Holten Johnsen
  • Patent number: 5795457
    Abstract: By applying two or more electrical fields (DC, AC, pulsed) of different characteristics to an electrode array on e.g. the wall of a treatment cell, particles suspended in liquid in the cell may be manipulated as desired on a microscopic scale, in particular by exploiting the dielectrophoretic properties of the particles. The particles may be solid, semi-solid or liquid, and may be of simple materials or may be biological particles such as whole cells or fragments thereof.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 18, 1998
    Assignee: British Technology Group Ltd.
    Inventors: Ronald Pethig, Julian Paul Hillhouse Burt
  • Patent number: 5789417
    Abstract: The invention relates to tricyclic compounds of formula (I) ##STR1## wherein R.sup.1 is hydrogen, amino, (1-4C)alkyl, (1-4C)alkoxy, hydroxy-(1-4C)alkyl or fluoro-(1-4C)alkyl; R.sup.2 is hydrogen, (1-4C)alkyl, (3-4C)alkenyl, (3-4C)alkynyl, hydroxy-(2-4C)alkyl, halogeno-(2-4C)alkyl or cyano-(1-4C)alkyl; Ar is optionally-substituted phenylene, thiophenediyl, thiazolediyl, pyridinediyl or pyrimidinediyl; and R.sup.3 includes a group of the formula --NHCH(CO.sub.2 H)--A.sup.1 --Y.sup.1 wherein A.sup.1 is (1-6C)alkylene and Y.sup.1 is carboxy, tetrazol-5-yl, N-?(1-4C)alkylsulphonyl!carbamoyl, N(phenylsulphonyl)carbamoyl, tetrazol-5-ylthio, tetrazol-5-ylsulphinyl or tetrazol-5-ylsulphonyl; or pharmaceutically-acceptable salts or esters thereof; to processes for their manufacture; to pharmaceutical compositions containing them; and to their use as anti-cancer agents.
    Type: Grant
    Filed: June 28, 1995
    Date of Patent: August 4, 1998
    Assignees: Zeneca Limited, British Technology Group Ltd.
    Inventors: Francis Thomas Boyle, James William Crook, Zbigniew Stanley Matusiak
  • Patent number: 5787185
    Abstract: A method of verifying the identity of an individual comprises capturing an image of the subcutaneous vein pattern at a predetermined region of the individual, converting the captured image to a plurality of stored values representative of the intensity of said image at specified relative locations, processing the stored values to produce a second plurality of stored values representative of the image of the vein pattern having enhanced contrast and subjecting the second plurality of stored values to a thresholding process to select those above a predetermined value and storing a set of measurements derived from the selected ones of said second plurality of stored values for comparison with a corresponding set of measurements made on the individual.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: July 28, 1998
    Assignee: British Technology Group Ltd.
    Inventor: David Oswald Clayden
  • Patent number: 5786089
    Abstract: Optically non-linear materials suitable upon repeated Langmuir-Blodgett dipping for forming Z-type (head-to-tail) films for second harmonic generation include hemicyanine dyes which are very unsymmetrical, i.e. which have hydrophobic substituents differing in size by at least 4 carbon atoms, each end of a hydrophilic chromophore. A suitable dye is E-N-octadecyl-4-?2-(4-dibutylaminophenyl)ethenyl!quinolinium iodide.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: July 28, 1998
    Assignee: British Technology Group Ltd.
    Inventor: Geoffrey Joseph Ashwell
  • Patent number: 5783199
    Abstract: A high pressure pre-mixed analgesic anaesthetic gas composition comprising a life supporting gas and a volatile analgesic anaesthetic mixture; characterised in that the mixture comprises a first and a second anaesthetic analgesic, said first analgesic having blood/gas solubility co-efficient .lambda. significantly in excess of the .lambda. of the second analgesic.
    Type: Grant
    Filed: March 7, 1997
    Date of Patent: July 21, 1998
    Assignee: British Technology Group Ltd.
    Inventors: John Alexander Strachen Ross, Michael Eric Tunstall
  • Patent number: 5773098
    Abstract: A thin fluoropolymer film is covalently bonded to a microporous ptfe film to make a bilayer for separation, filtration or reverse osmosis, by exposing the microporous film to perfluorocyclohexane under plasma. The perfluorocyclohexane molecules undergo scission and the fragments combine on the substrate to make a fluoropolymer film wherein the pores of the substrate have not been completely closed by the coating.
    Type: Grant
    Filed: November 21, 1995
    Date of Patent: June 30, 1998
    Assignee: British Technology Group, Ltd.
    Inventor: Thomas Ronald Thomas
  • Patent number: 5770856
    Abstract: The disclosed optical device includes a probe which is integrally supported on a cantilever which defines an optical path extending to an external device which may carry an optical processor.In a preferred embodiment the device has an optical path which is capable of guiding an evanescent wave to the external device. The device overcomes a problem with prior art Scanning Tunnelling Microscopes in that, by utilizing evanescent waves, it enables access to the so called mesoscopic range between approximately 1.times.10.sup.-10 m.rarw.50.times.10.sup.-10 m (1.ANG.-50.ANG.). In an alternative embodiment the invention permits manipulation of microscopic particles by utilising the probe. The probe may also act as a sensor.
    Type: Grant
    Filed: February 23, 1996
    Date of Patent: June 23, 1998
    Assignee: British Technology Group Ltd
    Inventors: Jean Pierre Fillard, Michel Castagne, Jacques Bonnafe
  • Patent number: 5762906
    Abstract: A structurally modified protein is provided that will bind to a tumor-associated structure wherein the amino group in at least one basic amino acid in the binding protein is structurally modified to convert the amino group, --NH.sub.2, to the grouping --NH--CO--X--NHR in which R is H or an amino protecting group and the grouping --CO--X--NHR is the residue of a peptide of the formula NHR--X--COOH capable of acting as a substrate for a phosphokinase.
    Type: Grant
    Filed: June 16, 1994
    Date of Patent: June 9, 1998
    Assignee: British Technology Group Ltd.
    Inventor: Andrew Malcolm Creighton
  • Patent number: 5733506
    Abstract: A gas sensor has a gas sensing component which permits measurement of a change in optical absorption and, optionally also a change in electrical conductivity on exposure to an environment containing certain gases. The gas sensing component comprises a metal bis aromatic macrocycle which may be a new mixed rare earth metal bis tetrabenzoporphyrin or tetrabenzoazaporphyrin.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: March 31, 1998
    Assignee: British Technology Group, Ltd.
    Inventors: Jack Silver, Kenneth Ralph Rickwood, Mustafa Tahsin Ahmet
  • Patent number: 5723016
    Abstract: An implantable prosthetic patellar component comprises a patellar part (1) having one side (1a) adapted to be secured to the inner surface of a natural patella (10), and a femoral part (3) having one side (5) defining an articulation surface to replace the femoral facet of the patella, the opposite surfaces (1b and 3a) of said parts being mutually engageable to afford sliding movement therebetween in a medio-lateral direction.The implant is able to accommodate relative medio-lateral movement and thereby improve congruency. It may be used in combination with other prosthetic components in a knee joint.
    Type: Grant
    Filed: November 17, 1995
    Date of Patent: March 3, 1998
    Assignee: British Technology Group Ltd.
    Inventors: Julian Richard Minns, Swee Chai Ang, Ian Wiliam Wallace
  • Patent number: 5719119
    Abstract: Parenteral nutrition aqueous solutions are provided which preferably contain glutamine together with other organic nitrogen containing compounds. The respective concentrations of the compounds present in any given such solution are typically approximately multiples of the concentration of the same compounds as found in normal human plasma, and the respective mole ratios of various such compounds in any given such solution relative to one another are approximately the same mole ratio associated with the same compounds as found in normal human plasma. Processes for using such solutions are provided.
    Type: Grant
    Filed: April 26, 1993
    Date of Patent: February 17, 1998
    Assignee: British Technology Group, Ltd.
    Inventor: Richard L. Veech
  • Patent number: 5718231
    Abstract: A laser ultrasound probe, suitable for intravascular use, of the kind having an ultrasonic transducer element comprising an ultrasound receiving surface of piezoelectric polymeric material and an optical fiber with one end directed forwardly from that surface and arranged to receive laser radiation for transmission through the optical fiber and emission from the said one end thereof, wherein the optical fiber is coupled with laser source means adapted to provide alternatively a relatively low average power laser beam, which, when modulated or pulsed and emitted from the one end of the optical fiber and incident on a target, will generate ultrasound at an intensity suitable to be received by the transducer element and converted thereby into electrical monitoring signals, and a relatively high average power laser beam suitable, when incident on the said target, to produce ablation thereof, the transducer element being sufficiently robust to withstand the ultrasound which is then also generated.
    Type: Grant
    Filed: February 20, 1996
    Date of Patent: February 17, 1998
    Assignee: British Technology Group Ltd.
    Inventors: Richard James Dewhurst, Peter Alfred Payne, Qing Xin Chen, Kok Fu Pang
  • Patent number: 5710101
    Abstract: The invention provides a composition for sustaining plant material comprising an aminopurine or a derivative or salt thereof and at least one water soluble sulfonated polyester or sulfonamide.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: January 20, 1998
    Assignee: British Technology Group Ltd.
    Inventors: Margaret Louise Carstairs, Laurence William Irvine Jennings
  • Patent number: RE35948
    Abstract: Pharmaceutical compositions containing a 3-hydroxypyrid-2-one or 3-hydroxypyrid one in which the hydrogen atom attached to the nitrogen atom is replaced by an aliphatic acyl group, by an aliphatic hydrocarbon group, or by an aliphatic hydrocarbon group substituted by one or, except in the case of ionizable groups, more than one substituent selected from aliphatic acyl, alkoxy, aliphatic amine, aliphatic amide, carboxy, aliphatic ester, halogen, hydroxy and sulpho groups and, optionally, in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by one of said substituents, by an aliphatic hydrocarbon group, or by an aliphatic hydrocarbon group substituted by an alkoxy, aliphatic ester, halogen or hydroxy group, but excluding compounds in which said replacement of hydrogen atoms in the compound is effected only by aliphatic hydrocarbon groups, or a salt thereof containing a physiologically acceptable ion or ions, are of value for removing toxic amounts of metals, particularly iron, f
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: November 3, 1998
    Assignee: British Technology Group Ltd.
    Inventors: Robert C. Hider, George Kontoghiorghes, Jack Silver
  • Patent number: RE36831
    Abstract: Pharmaceutical compositions containing an iron complex of a 3-hydroxypyrid-2-one or 3-hydroxypyrid-4-one in which the hydrogen atom attached to the nitrogen atom is replaced by an aliphatic acyl group, by an aliphatic hydrocarbon group, or by an aliphatic hydrocarbon group substituted by one or, except in the case of ionizable groups, more than one substituent selected from aliphatic acyl, alkoxy, aliphatic amine, aliphatic amide, carboxy, aliphatic ester, halogen, hydroxy and sulpho groups and, optionally, in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by one of said substituents, by an aliphatic hydrocarbon group, or by an aliphatic hydrocarbon group substituted by an alkoxy, aliphatic ester, halogen or hydroxy group, but excluding compounds in which said replacement of hydrogen atoms in the compound is effected only by aliphatic hydrocarbon groups, are of value for the treatment of iron deficiency anemia.
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: August 22, 2000
    Assignee: British Technology Group Ltd.
    Inventors: Robert C. Hider, George Kontoghiorghes, Jack Silver, Michael A. Stockham