Patents Assigned to Brittish Columbia Cancer Agency Branch
  • Bisphenol derivatives and their use as androgen receptor activity modulators
    Patent number: 9388112
    Abstract: This invention provides bisphenol derivatives having a structure of formula 1. Said compounds are modulators of the androgen receptor activity and are useful in the treatment of various diseases, including prostate cancer, breast cancer, ovarian cancer, endometrial cancer, acne, ovarian cysts, polycystic ovarian disease, age-related macular degeneration, precocious puberty, hirsutism and hair loss.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: July 12, 2016
    Assignees: The University of British Columbia, Brittish Columbia Cancer Agency Branch
    Inventors: Marianne D. Sadar, Nasrin R. Mawji, Carmen Adriana Banuelos, Raymond J. Andersen, Javier Garcia Fernandez