Abstract: The present disclosure relates to compositions and methods for manufacturing biomaterials that form flowable and injectable cold slurries. More particularly, the present disclosure relates to a composition containing a plurality of liposomes where the encapsulated internal liposomal media and external liposomal media have different freezing points.
Type:
Application
Filed:
July 23, 2020
Publication date:
September 1, 2022
Applicants:
The General Hospital Corporation, Brixton Biosciences, Inc.
Inventors:
Richard Rox Anderson, William Farinelli, Lilit Garibyan, Sameer Sabir, Charles Sidoti, Mansoor M. Amiji, Maie Taha
Abstract: Disclosed herein is a system for creating an injectable and flowable cold slurry, the system comprising a housing; a mount operatively connected to the housing configured to accept a container; a first motor configured to move the mount from a first position to a second position; a second motor; and a drive shaft in communication with the second motor, wherein the drive shaft is configured to rotate to cause an internal volume of the container to be transformed into the injectable and flowable cold slurry.
Type:
Grant
Filed:
April 2, 2021
Date of Patent:
February 8, 2022
Assignee:
Brixton Biosciences, Inc.
Inventors:
Sameer Sabir, Olivier Kagan, Charles Sidoti