Abstract: An article of apparel including an integrated fabric system, with or without strategically-placed weighting and/or elastic resistant materials, which optimizes conditioning, strengthening, endurance, enhancement, training, performance, functional longevity, benefits of daily activity, movement therapy, and/or other diverse medical and/or therapeutic uses, and, all while reducing the possibility of injury. The article enables the user to receive medical and/or therapeutic benefits and to increase production of kinetic energy, through weighted and/or elastic resistance, as required by the user's particularized needs. The user may benefit from the medical/therapeutic properties during periods of activity or inactivity. Benefits are achieved through the integration of fabrics and strategically-placed weighting and/or elastic resistance materials into the article based upon the kinetic energy created, necessitated, and/or dissipated by a specific movement(s) and/or medical or therapeutic requirements.