Abstract: The invention relates to the new, asymmetrically substituted derivatives of 2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione and their use as cytostatics exhibiting activity against tumor cells, especially against cells with multidrug resistance (MDR). In particular, the invention concerns derivatives of 2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione represented by the general formula (I).
Type:
Application
Filed:
April 13, 2012
Publication date:
January 30, 2014
Applicant:
BS-154 SP. Z O.O.
Inventors:
Edward Borowski, Barbara Stefanska, Maria Dzieduszycka, Marcin Cybulski, Wieslaw Szelejewski, Janusz Obukowicz, Maria Bontemps-Gracz, Malgorzata Wysocka, Jan Mazerski, Pawel Punda, Joanna Wietrzyk