Abstract: The invention relates to a pharmaceutical composition and in particular a dermal patch or wound dressing comprising an acid-hydrolyzing oligomer and/or polymer and an acid-activated prodrug such that the active principle in the pharmaceutical composition or in the dermal patch or wound dressing is formed from the prodrug under the effect of acid. The invention further relates to a corresponding method for releasing active principles from a pharmaceutical composition.

Abstract: The present invention relates to a silicone-gel-coated, adhesive layer structure, a method for the production thereof as well as the use thereof. The layer structure comprises a porous backing material, an intermediate layer applied to one side of the porous backing material and an adhesive layer made of a silicone gel applied to the intermediate layer.

Abstract: An orthosis for fastening to a human hand for immobilizing the carpometacarpal joint and metacarpophalangeal joint of the thumb of the hand has a stiff body which can be of multi-piece or single-piece design. The rigidity of the body enables the latter to support, to stabilize and to immobilize the hand and dimensional stability is provided such that the body can be placed in a simple manner with a defined shape onto the hand.

Abstract: A wound care device for the treatment of wounds is disclosed by means of atmospheric negative pressure in the wound region, including a wound-covering element that can be attached to the skin of a patient as well as a connection device for the suctioning of fluid media, wherein the wound-covering element includes a window that can be opened, which window is arranged on the wound-covering element by means of a gas-tight closure.

Abstract: The invention relates to a wound care article relates having at least one flat layer consisting of a woven fabric or nonwoven comprising superabsorbent fibers and superabsorbent particles.

Abstract: The present invention relates to a medical bathing equipment for the manufacture and use of a bathing solution containing an active substance and in particular a bathing solution containing NO. The invention also relates to a bathing equipment based on a multi-stage method for generating NO and the bathing equipment in its use for the treatment of diseases, in particular of diabetically caused circulatory disorders and wounds of the lower extremities.

Abstract: An NO-accumulation apparatus, method and use, comprising: a container (120) defining a cavity for accommodating a liquid (105), an inlet (150) for feeding the liquid into the container (120) and an outlet (151) for delivering the liquid from the container (120) to a bath unit; an NO-gas dissolving unit (140) for dissolving gaseous NO in the liquid (105) to produce an NO-containing liquid, wherein the NO-gas dissolving unit (140) is arranged in the container (120) and/or forms a part of the container (120); and an NO-gas port (110) in fluid communication with the NO-gas dissolving unit (140), wherein the NO-gas port (110) is adapted for coupling, particularly for releasably coupling, with an NO-gas supply, whereby the apparatus further comprises means for decoupling the inflow of NO to the liquid (105) within the container from the removal of the NO-containing liquid (NO-decoupling means), so that the removal of the NO-containing liquid is inhibited, when the NO is flowing into the liquid, and also the NO infl

Abstract: The present invention relates to a fluid-permeable primary dressing in strip form, having pores, perforations or honeycomb lattices, which enable the passage of fluid, further having a coating of a material comprising silicone.

Abstract: A closure is shown and described, preferably for an orthosis, which has a belt assembly, having a first closure part (1) and a second closure part (21), which can be releasably connected to one another, wherein the first and the second closure parts (1, 21) have connecting means for belts of the belt assembly, wherein the first closure part (1) has a pin (3), wherein the second closure part (21) has a connection end (23) and a coupling end (25), and between the connection end (23) and the coupling end (25) a guide track (37) extending in a closure plane is provided, which extends from an entrance opening (41) to a guide track end (43), wherein the pin (3) has a first section (7) and a second section (9), wherein the dimensions of the first section (7) perpendicular to the direction of extension of the pin (3) correspond to the dimensions of the guide track (37) in the closure plane at the guide track end (43), and wherein the dimensions of the second section (9) perpendicular to the direction of extension of

Abstract: The present invention relates to a medical dressing that has a modular structure consisting of at least two layers and that is able to cleave incorporated photolabile nitric oxide donors in an adjoining absorption module by means of the emission of electromagnetic radiation from a light module, so that the photolytically generated nitric oxide can be used to enhance medical therapies in humans and animals as well as to generate NO.

Abstract: A multi-layered wound care product includes an upper liquid-absorbing layer, an intermediate occlusive layer; and an active agent-releasing bottom layer. The latter two layers have common pores or perforations that enable the passage of wound exudate through the two layers to reach the liquid-absorbing layer. A use of the multi-layered wound care product for treatment of acute and chronic wounds and a method of producing the multi-layered wound care product are also provided.

Abstract: The present invention relates to a reel for a plaster strip roll with one or two side discs and/or a cover/protective ring for a plaster strip roll, which optionally has a tear-off edge, as well as the production thereof. The reel or the cover/protective ring, respectively, comprises an antimicrobially effective substance, wherein, on the outer surface of the reel or of the cover/protective ring, respectively, there is contact between the antimicrobially effective substance and the environment.

Abstract: The invention relates to a flat wound care article having an essentially polygonal or ellipsoid base surface and at least one recess arranged on one side.

Abstract: The invention relates to an absorbent article for application to human or animal skin surfaces in the region of wounds, consisting of an outer covering (2) which is permeable for liquid substances, and of an inner layer (1) which is surrounded by the covering (2) and which consists essentially of a mixture of an amount of strongly osmotically active substances with an amount of osmotically comparatively weak or osmotically inactive substances, such as cellulose. The inner layer (1) is filled with osmotically active substances in such a way that it is possible to exert on a wound, with the wound fluids contained therein, an osmotic pressure via which the wound fluid can be removed from the organism to be treated, and thus it is possible to assist both in the surfaced wound region and in the depth of the tissue a normal interstitial hydration of tissue by directing endogenous fluids in their direction of flow to the patient's skin surface into the absorbent article, and keeping them there.

Abstract: The present invention relates to a wound-covering article (10) having a film-like element (11) of reduced gas permeability, wherein said film-like element has a preparation (12) for attachment of a vacuum device.

Abstract: An absorbent article that includes an outer covering made of two liquid-permeable cover layers that are joined together to form a pocket, and an inner layer that is initially freely movable within the pocket. The inner layer includes a mixture of particles of a superabsorbent polymer and substances that are osmotically comparatively weaker than the particles. When the absorbent article is applied to a human or animal skin surface to cover a wound, the absorbent article exerts an osmotic pressure via which endogenous wound exudate is removed from the wound. Thus, the absorbent article assists, both in a surface region and in a tissue depth, a normal interstitial hydration of the tissue by directing the wound fluids in a direction of flow to the skin surface and into the absorbent article, and by keeping the wound fluids that flow to the skin surface in the absorbent article.

Abstract: An orthosis for fastening to a human hand for immobilizing the carpometacarpal joint and metacarpophalangeal joint of the thumb of the hand has a stiff body which can be of multi-piece or single-piece design. The rigidity of the body enables the latter to support, to stabilize and to immobilize the hand and dimensional stability is provided such that the body can be placed in a simple manner with a defined shape onto the hand.