Patents Assigned to Buckman Laboratories International Inc.
  • Patent number: 6110950
    Abstract: Microbicidal compositions containing synergistic combinations of propiconazole, (RS)-1-2-[(2,4-dichlorophenyl)-2-propyl-1,3-dioxalan-2ylmethyl]-1H-1,2,4-t riazole, and 2-mercaptobenzothiazole or alkali metal salt thereof are described. The propiconazole and 2-mercaptobenzothiazole or an alkali metal salt thereof are applied to a substrate or aqueous system subject to the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described. The combination of propiconazole and 2-mercaptobenzothiazole or an alkali metal salt thereof is particularly useful as microbicidal in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in industrial process waters.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: August 29, 2000
    Assignee: Buckman Laboratories International Inc.
    Inventor: Allan Saroj Pillay
  • Patent number: 6110452
    Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one polyglycol fatty acid ester to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one polyglycol fatty acid ester to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The present invention also relates to a composition containing polyglycol fatty acid esters and useable in the above methods. The compositions comprise at least one polyglycol fatty acid ester in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: August 29, 2000
    Assignee: Buckman Laboratories International Inc
    Inventors: Daniel E. Glover, Marilyn S. Whittemore, Stephen D. Bryant
  • Patent number: 6103666
    Abstract: Compositions comprising an ionene polymer and a salt of dodecylamine are disclosed which are synergistically effective compared to the respective components alone in controlling the growth of microorganisms in or on a material or medium. Methods to control the growth of microorganisms with the use of the compositions of the present invention are also disclosed.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: August 15, 2000
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Fernando Del Corral, Percy Jaquess, David Oppong
  • Patent number: 6103131
    Abstract: The invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one sulfamic acid or salt thereof to inhibit bacterial adhesion to the submergible surface. The invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one sulfamic acid or salt thereof to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The sulfamic acid used in the method of the invention has the formula R.sup.1 R.sup.2 NS(O).sub.2 (OH). In this formula, R.sup.1 and R.sup.2 are independently a hydrogen, a C.sub.4 -C.sub.20 alkyl group or a cyclohexyl group. However, R.sup.1 and R.sup.2 are not both hydrogen. Alternatively, R.sup.1 and R.sup.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: August 15, 2000
    Assignee: Buckman Laboratories International Inc.
    Inventors: Thomas E. McNeel, Marilyn S. Whittemore, Stephen D. Bryant, Graciela H. Vunk
  • Patent number: 6075022
    Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one thiourea to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one thiourea to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bactaria. The thiourea used in the method of the invention has the following formula a compound of the formula: The present invention also relates to compositions containing thiourea compounds and useable in the above methods. The compositions comprise at least one thiourea in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: June 13, 2000
    Assignee: Buckman Laboratories International Inc.
    Inventors: Mark L. Zollinger, Stephen D. Bryant
  • Patent number: 6060466
    Abstract: Microbicidal compositions are described. The compositions comprise (a) 2-(Thiocyanomethylthio)benzothiazole (TCMTB) and (b) an N-alkyl heterocyclic compound of the formula: ##STR1## The variable "n" ranges from 5 to 17, and the heterocyclic ring defined by ##STR2## is a substituted or unsubstituted ring having four to eight members. Components (a) and (b) are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates or in aqueous systems are also described. Also described is the industrial application of the microbicidal composition in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in aqueous systems.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: May 9, 2000
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Marilyn S. Whittemore, Daniel E. Glover, S. Rao Rayudu, Dean T. Didato
  • Patent number: 6034081
    Abstract: A method for increasing the effectiveness of a microbicide is described, wherein a microbicide and an N-alkyl heterocyclic compound are applied to a substrate or aqueous system subject to the growth of microorganisms. The N-alkyl heterocyclic compound is applied in an amount effective to increase the microbicidal activity of the microbicide. The N-alkyl heterocyclic compound has the formula: ##STR1## The variable "In" ranges from 5 to 17, and the heterocyclic ring defined by ##STR2## is a substituted or unsubstituted ring having four to eight members. Microbicidal compositions are described where the microbicide and the N-alkyl heterocyclic compound are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: March 7, 2000
    Assignee: Buckman Laboratories International Inc
    Inventors: Marilyn S. Whittemore, Daniel E. Glover, S. Rao Rayudu
  • Patent number: 6030971
    Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one amide to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one amide to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bacteria. The amide used in the method of the invention has the following formula: ##STR1## The present invention also relates to compositions containing amides and useable in the above methods. The compositions comprise at least one amide in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: February 29, 2000
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Marilyn S. Whittemore, Daniel E. Glover, Mark L. Zollinger, Stephen D. Bryant
  • Patent number: 6008236
    Abstract: Compositions comprising an ionene polymer and a pyrithione salt are disclosed which are synergistically effective compared to the respective components alone in controlling the growth of microorganisms in or on a material or medium. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: December 28, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventors: David Oppong, Russel E. Fues, Graciella H. Canullo
  • Patent number: 5962555
    Abstract: ASA sizing emulsions containing low and high molecular weight cationic polymers are described. An ASA sizing emulsion of the invention contains 25 to 99 percent by weight water, 0.003 to 60 percent by weight ASA, 0.003 to 50 percent by weight of a cationic polymer mixture, and 0 to 2 percent by weight of a surfactant. The cationic polymer mixture contains 75 to 99 percent by weight of an ionene polymer and 1 to 25 percent by weight of a high molecular weight polyethyleneimine polymer. In the sizing emulsion, the ASA has a particle size ranging from 0.5 to 3 microns. A method for sizing paper using such an emulsion is also described.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: October 5, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventor: Daniel E. Glover
  • Patent number: 5929073
    Abstract: Compositions for controlling the growth of microorganisms in or on a product, material, or medium comprising synergistically effective amounts of (a) dodecylmorpholine or a salt thereof and (b) dodecylamine or a salt thereof are disclosed. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: July 27, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventors: David Oppong, Percy A. Jaquess, Fernando Del Corral, Marilyn S. Whittemore
  • Patent number: 5925616
    Abstract: A method for increasing the effectiveness of an anti-fungal compound is described. In the method, an anti-fungal compound and an N-alkyl heterocyclic compound or a salt thereof are administered to a mammal in a combined amount effective to treat a fungal infection. The N-alkyl heterocyclic compound or salt thereof is present in an amount effective to potentiate or increase the anti-fungal activity of the anti-fungal compound. The N-alkyl heterocyclic compound has the formula: ##STR1## The variable "n" ranges from 5 to 17, and the heterocyclic ring defined by ##STR2## is a substituted or unsubstituted ring having four to eight members. A pharmaceutical composition is described where the anti-fungal compound and the N-alkyl heterocyclic compound or salt thereof are present in a combined amount effective to treat a fungal infection.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: July 20, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventor: Marilyn S. Whittemore
  • Patent number: 5902808
    Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The N-alkyl heterocyclic compound used in the method of the invention has the following formula: ##STR1## The substituent R.sup.1 is a C.sub.8 -C.sub.20 alkyl group. The heterocyclic ring is a 5-8 membered heterocyclic ring where X is O, NH, or CH.sub.2. R.sup.2 is methyl, hydroxymethyl, or hydroxyethyl. The integer n ranges from 0 to 3.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: May 11, 1999
    Assignee: Buckman Laboratories International Inc.
    Inventors: Marilyn S. Whittemore, Daniel E. Glover, Joe C. Steelhammer, Stephen D. Bryant
  • Patent number: 5902820
    Abstract: Microbicidal compositions are described. The compositions contain (a) propiconazole and (b) dodecylamine or a dodecylamine salt. The propiconazole and dodecylamine or dodecylamine salt are present in a synergistically effective amount to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates or in aqueous systems are also described. Also described is the industrial application of the microbicidal composition in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in aqueous systems.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: May 11, 1999
    Assignee: Buckman Laboratories International Inc.
    Inventors: Percy A. Jacquess, David Oppong, Sheldon M. Ellis, L. Fernando Del Corral
  • Patent number: 5888405
    Abstract: The invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one amino methyl phosphonic acid or salt thereof to inhibit bacterial adhesion to the submergible surface. The invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one amino methyl phosphonic acid or salt thereof to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The amino methyl phosphonic acid used in the methods of the invention has the formula R.sup.1 R.sup.2 NCH.sub.2 P(O)(OH).sub.2. In this formula, R.sup.1 and R.sup.2 are independently a C.sub.6 -C.sub.20 alkyl group or a CH.sub.2 P(O)(OH).sub.2 group. However, R.sup.1 and R.sup.2 are not both a CH.sub.2 P(O)(OH).sub.2 group. Alternatively, R.sup.1 and R.sup.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: March 30, 1999
    Assignee: Buckman Laboratories International Inc.
    Inventors: Thomas E. McNeel, Marilyn S. Whittemore, Stephen D. Bryant, Graciela H. Vunk
  • Patent number: 5879623
    Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one fluorosurfactant to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one fluorosurfactant to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bacteria fouling organisms. The fluorosurfactant used in the method of the invention is an anionic or nonionic fluorosurfactant selected from: R.sub.f CH.sub.2 CH.sub.2 SCH.sub.2 CH.sub.2 CO.sub.2 Li, (R.sub.f CH.sub.2 CH.sub.2 O)P(O) (ONH.sub.4).sub.2, (R.sub.f CH.sub.2 CH.sub.2 O).sub.2 P(O) (ONH.sub.4), (R.sub.f CH.sub.2 CH.sub.2 O)P(O) (OH).sub.2, (R.sub.f CH.sub.2 CH.sub.2 O).sub.2 P(O) (OH), R.sub.f CH.sub.2 CH.sub.2 O (CH.
    Type: Grant
    Filed: December 27, 1995
    Date of Patent: March 9, 1999
    Assignee: Buckman Laboratories International Inc.
    Inventors: Daniel E. Glover, Joe C. Steelhammer, Stephen D. Bryant
  • Patent number: 5874453
    Abstract: Compositions comprising a mixture of 2-(thiocyanomethylthio)benzothiazole and methylene-bis(thiocyanate) with dimethylamide of a carboxylic acid are disclosed which are synergistically effective compared to the respective components alone in controlling the growth of microorganisms in or on a product, material, or medium. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: February 23, 1999
    Assignee: Buckman Laboratories International, inc.
    Inventors: David Oppong, Vanja M. King
  • Patent number: 5869655
    Abstract: A diamine useful as a catalyst for the polymerization of urethane. A method of making the catalyst comprises reacting a spiro quaternary amine with a secondary amine. The spiro quaternary amine is also useful as an antimicrobial agent.
    Type: Grant
    Filed: November 5, 1993
    Date of Patent: February 9, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Wallace E. Puckett, Mark L. Zollinger
  • Patent number: 5866016
    Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an ionene polymer and a salt of dodecylamine in a combined amount effective to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an ionene polymer and a salt of dodecylamine in a combined amount effective to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The present invention also relates to compositions containing an ionene polymer and a salt of dodecylamine and useable in the above methods. The compositions comprise an ionene polymer and a salt of dodecylamine in a combined amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
    Type: Grant
    Filed: July 1, 1997
    Date of Patent: February 2, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Percy A. Jaquess, Luis Fernando Del Corral, Richard A. Clark
  • Patent number: 5859040
    Abstract: Compositions comprising a compound of formula I ##STR1## where R and R' are independently selected from hydrogen and alkyl of 1 to 4 carbon atoms, R" is a moiety selected from the group consisting of (a) hydrogen, (b) a halogen atom selected from the group consisting of F, Cl, Br, and I, and (c) a nitro group, or the hydrochloride salt of said compound; and at least one preservative are disclosed which are synergistically effective compared to the respective components alone in controlling and/or reducing the growth of microorganisms in or on a material or medium. Methods to control and/or reduce the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: January 12, 1999
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Vanja M. King, Xiangdong Zhou