Patents Assigned to Bundesrepublik Deutschland last Represented by the President of the Paul-Ehrlich-Instituts
  • Retroviral vectors, methods for their preparation and their use for gene transfer into CD4-positive cells
    Patent number: 6902929
    Abstract: The invention relates to the production and use of retroviral vectors for cell specific gene transfer, specially to a production method of retroviral vectors containing capsid particles of murine leukemia virus (MLV) and envelope proteins of human immunodeficiency vises (HIV) or simian immunodeficiency viruses (SIV). Said vectors can be used for gene transfer in selected cell types, specially in CD4-positive mammal cells.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: June 7, 2005
    Assignee: Bundesrepublik Deutschland last Represented by the President of the Paul-Ehrlich-Instituts
    Inventors: Klaus Cichutek, Jorn Stitz