Abstract: A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein.
Type:
Grant
Filed:
June 3, 2014
Date of Patent:
February 18, 2020
Assignee:
C&C Research Laboratories
Inventors:
Chan Hee Park, Sang Hwi Lee, Junhwan Im, Soon Ok Lee, Hoe Moon Kim, Sung Hyun Moon, Seunghee Kim, Jongmin Kim, Kwang Seok Ko, Bu Young Choi, Byungho Kim
Abstract: Disclosed are heterocyclic derivatives, and more particularly heterocyclic derivatives having the following Formula I which are useful for the preparation of medicaments for treating diseases related to uric acid: wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X3, L and Y are the same as defined in the detailed description.
Type:
Grant
Filed:
March 31, 2009
Date of Patent:
March 12, 2013
Assignee:
C&C Research Laboratories
Inventors:
Sung Oh Ahn, Chan Hee Park, Jun Hwan Im, Soon Ok Lee, Kyoung June Lee, Seong Wook Cho, Kwang Seok Ko, Sun Young Han, Won Il Lee
Abstract:
The present invention relates to a novel thrombin inhibitor which is effective even when orally administered. More specifically, the present invention relates to an aromatic amidine derivative represented by formula (I) and the salts thereof, which show potent selective inhibitory activity for thrombin in which (a), R, R1, R2, R3, A, W, Y and n are defined as described in the specification.
Type:
Grant
Filed:
November 13, 1998
Date of Patent:
March 13, 2001
Assignee:
C & C Research Laboratories
Inventors:
Bon Am Koo, Jae Ki Min, Woo Sang Hong, Eun Jung Ryu, Woong Hyun Nam, Jong Min Kim