Abstract: A control method for controlling injection of an engine having an oxygen concentration sensor generating a composition signal as a function of the oxygen difference in the exhaust gases with respect to the stoichiometric condition of the burnt air/fuel mixture, and a number of injectors for injecting fuel for an operating injection time in each operating state of the engine, and each of which is assigned, in each operating state of the engine, a respective calibration injection time determined at an initial engine calibration stage using a reference fuel.