Abstract: This patent discloses a substituted fullerenes, compositions comprising the same, and their use as antioxidants. The substituted fullerenes comprise a fullerene core (Cn) and at least one of: (i) from 1 to 6 (>CX1X2) groups bonded to the fullerene core; (ii) from 1 to 18 —X3 groups bonded to the fullerene core; (iii) from 1 to 6 —X4— groups bonded to the fullerene core; or (iv) from 1 to 6 dendrons bonded to the fullerene core.
Type:
Grant
Filed:
October 7, 2004
Date of Patent:
January 16, 2007
Assignee:
C Sixty Inc.
Inventors:
Stephen R. Wilson, Yi-Zhen Hu, Tong Zhu, Russ Lebovitz
Abstract: Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layers of the vesicle wall, (ii) a substituted fullerene, comprising a fullerene core and a functional moiety, wherein the therapeutic agent is associated with the substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic agent is covalently bonded to the carbon nanotubes.
Type:
Grant
Filed:
February 14, 2003
Date of Patent:
July 4, 2006
Assignee:
C Sixty Inc.
Inventors:
Andreas Hirsch, Uri Sagman, Stephen R. Wilson