Abstract: Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed.
Type:
Application
Filed:
July 23, 2018
Publication date:
November 15, 2018
Applicant:
Cadent Therapeutics, Inc.
Inventors:
David R. Anderson, Robert A. Volkmann, Frank S. Menniti
Abstract: Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed.
Type:
Grant
Filed:
November 23, 2016
Date of Patent:
August 21, 2018
Assignee:
CADENT THERAPEUTICS, INC.
Inventors:
David R. Anderson, Robert A. Volkmann, Frank S. Menniti
Abstract: Provided are compounds of the formula: and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with potassium channels.
Type:
Grant
Filed:
January 23, 2018
Date of Patent:
May 22, 2018
Assignee:
Cadent Therapeutics, Inc.
Inventors:
Dipak Vasantrao Amrutkar, Kelly Foster, Thomas Amos Jacobsen, Martin R. Jefson, Gregg F. Keaney, Janus Schreiber Larsen, Karin Sandager Nielsen