Abstract: Provided herein are methods and systems for detecting and/or sorting targets in a sample based on the combined use of polynucleotide-encoded protein and substrate polynucleotides. The polynucleotide-encoded protein is comprised of a protein that specifically binds to a predetermined target and of an encoding polynucleotide that specifically binds to a substrate polynucleotide, wherein the substrate polynucleotide is attached to a substrate.
January 4, 2010
Date of Patent:
January 15, 2013
Cal. Inst. Tech.
Gabriel A. Kwong, Ryan C. Bailey, Rong Fan, James R. Heath