Abstract: A lung isolation tube assembly includes a control valve that is adapted to be moved between a left lumen position, a right lumen position, and a both lumens position, a connector that is in fluid communication with the control valve and having a port, and a tube that is in fluid communication with the connector. The tube includes a left lumen that is in fluid communication with the connector and a right lumen that is in fluid communication with the connector. The assembly also includes a first cuff that is disposed around a portion of the right lumen and the left lumen and a second cuff that is disposed around the left lumen. The assembly is adapted to convey airflow or oxygen to a human lung via at least one of the left lumen and the right lumen. A method for isolating a human long.