Abstract: Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.
Type:
Grant
Filed:
March 7, 2014
Date of Patent:
June 21, 2016
Assignees:
CALIFIA BIO, INC., UNIVERSITY OF ROCHESTER
Inventors:
Val S. Goodfellow, Thong X. Nguyen, Satheesh B. Ravula, Harris A. Gelbard
Abstract: Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.
Type:
Application
Filed:
March 7, 2014
Publication date:
September 11, 2014
Applicant:
Califia Bio, Inc.
Inventors:
VAL S. GOODFELLOW, THONG X. NGUYEN, SATHEESH B. RAVULA, HARRIS A. GELBARD