Abstract: A III-nitride optoelectronic device includes at least one n-type layer, an active region grown on or above the n-type layer, at least one p-type layer grown on or above the active region, and a tunnel junction grown on or above the p-type layer. A conductive oxide may be wafer bonded on or above the tunnel junction, wherein the conductive oxide comprises a transparent conductor and may contain light extraction features on its non-bonded face. The tunnel junction also enables monolithic incorporation of electrically-injected and optically-pumped III-nitride layers, wherein the optically-pumped III-nitride layers comprise high-indium-content III-nitride layers formed as quantum wells (QWs) that are grown on or above the tunnel junction. The optically-pumped high-indium-content III-nitride layers emit light at a longer wavelength than the electrically-injected III-nitride layers.

Abstract: An improved system and methods for enhancing the imaging of cameras included with wireless mobile devices, such as cellular phone or tablets. The imaging system includes a releasable optical attachment for imaging skin surfaces and cavities of the body. The releasable optical attachment comprises optical enhancement elements such as magnifying lenses, illumination diverting elements, and filters. Images can be viewed and analyzed on the mobile device, or transmitted to another location/device for analysis by a person or software. The results can be used to provide diagnosis, or for a variety of other applications including image comparison over time and product recommendations.

Abstract: Embodiments of the present systems and methods may provide imaging techniques for multidirectional imaging, light conditioning, illumination sequences, or machine learning to create algorithms created from training by other advanced imaging techniques. In an embodiment, a method for generating an image may comprise obtaining an image of an object produced by a camera and generating, from the obtained image produced by a conventional camera, using an artificial intelligence model and imaging process, an output image including additional information similar to additional information present in an image of the object produced by an advanced imaging system.

Abstract: The present invention provides a method for selective delivery of a therapeutic or diagnostic agent to a targeted organ or tissue by implanting a biocompatible solid support in the patient being linked to a first binding agent, and administering a second binding agent to the patient linked to the therapeutic or diagnostic agent, such that the therapeutic or diagnostic agent accumulates at the targeted organ or tissue.

Abstract: A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure.

Abstract: Reflectin proteins are proteins derived from cephalopods (certain species of squid) which have unusual optical properties. Disclosed herein are thin films of reflectin proteins which can be tuned to reflect infrared light. Advantageously, the films can be tuned dynamically over short time scales, to reflect at different wavelengths. Disclosed herein are novel infrared-reflective coatings, methods of making such coatings, and infrared-reflective objects such as textiles, building materials, and camouflage materials.

Abstract: A folding container assembly has a soft-sided wall structure that is collapsible from either a fully expanded condition or from a partially expanded condition, wherein the container assembly defines an interior chamber for storing articles, into a carry pouch format wherein the container assembly is folded down on itself such that the interior chamber of the container assembly is not accessible for use. Accordingly, the folding container assembly has a first configuration wherein the container assembly defines a first interior cavity having a first interior volume for storing articles, a second configuration wherein the container assembly defines a second interior cavity having a second interior volume, wherein the second interior volume is less than the first interior volume, and a third configuration wherein the container assembly is folded down on itself into a compact form such that the interior cavity or chamber is not accessible for use.

Abstract: Methods for predicting patient deterioration or clinical events by detecting patterns in heterogeneous temporal clinical data streams that are predictive of certain clinical end points and matching the patient state with those patterns are described. The detected patterns, referred to as SuperAlarm triggers, are a predictive combination of frequently co-occurring monitor alarms, conditions and laboratory test results that can predict patient deterioration for imminent life-threatening events. SuperAlarm triggers may also exhibit patterns in the sequence of SuperAlarms that are triggered over the monitoring time of a patient. Sequential patterns of SuperAlarm triggers may also indicate a temporal process of change in patient status. SuperAlarm based alerts will also greatly reduce the number of false alarms and alarm fatigue compared to conventional alarms.

Abstract: Provided herein, inter alia, are methods and compounds for inhibiting mTORC1 and for treating diseases associated with mTORC1 activity.

Abstract: A security primitive for an integrated circuit comprises an array of floating-gate transistors monolithically integrated into the integrated circuit and coupled to one another in a crossbar configuration. The floating-gate transistors have instance-specific process-induced variations in analog behavior to provide one or more reconfigurable physically unclonable functions (PUFs).

Abstract: Systems and methods of determining physical conditions of a battery, such as state of charge (SOC), state of health (SOH), quality of construction, defect, or failure state include driving two or more acoustic signals of two or more amplitudes, each acoustic signal having two or more frequencies, into the battery and detecting vibrations generated in the battery based on the two or more acoustic signals. Nonlinear response characteristics of the battery for the two or more acoustic signals are determined from the detected vibrations. The physical conditions of the battery are determined based at least in part on the nonlinear response characteristics, using nonlinear acoustic resonance spectroscopy (NARS) or nonlinear resonant ultrasound spectroscopy (NRUS).

Abstract: Techniques, systems, and devices are disclosed for implementing light-emitting hyperbolic metasurfaces. In one exemplary aspect, a light-emitting device includes a surface; a plurality of quantum heterostructures positioned on the surface, each of the plurality of quantum heterostructures including multiple quantum wells distributed along an axis perpendicular to the surface and separated by multiple quantum barriers, wherein each two adjacent quantum heterostructures of the plurality quantum heterostructures form a gap; and a monocrystalline material at least partially filling gaps between the plurality quantum heterostructures.

Abstract: Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin of a patient or the surface of a structure such as a building or a bridge.

Abstract: A heterodyne optical spectroscopy system comprises a light source that acts as a local oscillator (LO); a beam splitting component that generates a reference beam from the LO; a signal component that generates a sample signal from a sample; a beam blocker that can turn off the sample signal to generate blank shots; a composite signal detection subsystem that detects a heterodyned signal that is a mix of the sample signal and a portion of the LO; a composite reference detection subsystem synchronized to the signal detection subsystem to detect a portion of the reference beam; and a processor that processes digital signals from the signal detection subsystem and the reference detection subsystem. A very versatile reference scheme is developed to treat different heterodyne spectroscopies in a unified way, which achieves optimal noise suppression.

Abstract: The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed.

Abstract: In one aspect, there is provided a display. The display may include a waveguide layer, a first active layer, a redirecting layer, and a lenset layer.

Abstract: An apparatus for individually trapping atoms, individually imaging the atoms, and individually cooling the atoms to prevent loss of the atoms from the trap caused by the imaging. The apparatus can be implemented in various quantum computing, sensing, and metrology applications (e.g., in an atomic clock).

Abstract: A temperature sensor is described, which includes a sensor gel having a polymer, water and ions, and a first and a second electrode separated from each other by the sensor gel. The present disclosure further relates to a system which has a temperature sensor, a voltage source or electric current source, and a measurement device for detecting voltage or electric current. The present disclosure further relates to a bolometer and a temperature sensor array. A method for temperature detection is also described, wherein a temperature sensor is provided, a voltage or an electric current between the first electrode and the second electrode of the temperature sensor is provided, an electric current or a voltage between the first electrode and the second electrode is measured, and a temperature is determined from the measured electric current or voltage.

Abstract: This disclosure provides non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries. In certain embodiments the method involves administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces the desired locomotor activity.

Abstract: A computer-implemented method according to one embodiment includes identifying a plurality of two-dimensional (2D) images illustrating a subject performing a rotation, selecting a representative image of the subject, cropping the plurality of 2D images, utilizing the representative image of the subject, to create a cropped plurality of 2D images, aligning each of the cropped plurality of 2D images, thereby creating an aligned plurality of 2D images, selecting a subset of the aligned plurality of 2D images that illustrate a predetermined amount of rotation of the subject, and creating a three-dimensional (3D) point cloud of the subject, utilizing the subset of the aligned plurality of 2D images.