Patents Assigned to CALIWAY BIOPHARMACEUTICALS CO., LTD.
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Patent number: 11433034Abstract: The present invention provides a pharmaceutical composition for reducing localized fat, comprising drug-containing micelles made of surfactants, and curcumin encapsulated in said drug-containing micelles. This pharmaceutical composition for reducing localized fat can reduce the fat at the administration site, and has the advantages of high stability, high bioavailability for fat tissue, few side effects, and sustained release.Type: GrantFiled: January 22, 2020Date of Patent: September 6, 2022Assignee: Caliway Biopharmaceuticals Co., Ltd.Inventor: Yu-Fang Ling
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Patent number: 11318110Abstract: The present invention provides a pharmaceutical composition for reducing localized fat, comprising drug-containing micelles made of surfactants, and curcumin encapsulated in said drug-containing micelles. This pharmaceutical composition for reducing localized fat can reduce the fat at the administration site, and has the advantages of high stability, high bioavailability for fat tissue, few side effects, and sustained release.Type: GrantFiled: January 22, 2020Date of Patent: May 3, 2022Assignee: Caliway Biopharmaceuticals Co., Ltd.Inventor: Yu-Fang Ling
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Publication number: 20200338152Abstract: The present invention provides a subcutaneous injection formulation for reducing body weight. The subcutaneous injection formulation for reducing body weight comprises drug-containing micelles made of a polyoxyethylene castor oil derivative or polyoxyethylene castor oil derivatives, and a curcuminoid or curcuminoids encapsulated in the drug-containing micelles. The subcutaneous injection formulation for reducing body weight can reduce body weight and visceral fat on overweight or obese subjects, and has the advantages of low dosage, high stability, high fat tissue bioavailability, few side effects, and sustained release.Type: ApplicationFiled: July 10, 2020Publication date: October 29, 2020Applicant: Caliway Biopharmaceuticals Co., Ltd.Inventor: Yu-Fang Ling
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Publication number: 20200230102Abstract: Provided is a plant extract composition and a pharmaceutical composition thereof for reducing body weight and body fat, wherein the plant extract composition comprises a green tea extract and a turmeric extract respectively 30 wt % to 75 wt % and 20 wt % to 55 wt % of a total weight of the composition. In diet-induced obesity models, either obesity is induced first or simultaneously with administration, the plant extract composition and a pharmaceutical composition thereof can reduce body weight and body fat more significantly than a single plant extract or commercially available weight loss drugs.Type: ApplicationFiled: November 18, 2019Publication date: July 23, 2020Applicant: Caliway Biopharmaceuticals Co., Ltd.Inventor: Yu-Fang LING
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Patent number: 10716824Abstract: The present invention provides a subcutaneous injection formulation for reducing body weight. The subcutaneous injection formulation for reducing body weight comprises drug-containing micelles made of a polyoxyethylene castor oil derivative or polyoxyethylene castor oil derivatives, and a curcuminoid or curcuminoids encapsulated in the drug-containing micelles. The subcutaneous injection formulation for reducing body weight can reduce body weight and visceral fat on overweight or obese subjects, and has the advantages of low dosage, high stability, high fat tissue bioavailability, few side effects, and sustained release.Type: GrantFiled: August 25, 2017Date of Patent: July 21, 2020Assignee: Caliway Biopharmaceuticals Co., Ltd.Inventor: Yu-Fang Ling
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Patent number: 10610496Abstract: The present invention provides a pharmaceutical composition for reducing localized fat, comprising drug-containing micelles made of surfactants, and curcumin encapsulated in said drug-containing micelles. This pharmaceutical composition for reducing localized fat can reduce the fat at the administration site, and has the advantages of high stability, high bioavailability for fat tissue, few side effects, and sustained release.Type: GrantFiled: August 26, 2016Date of Patent: April 7, 2020Assignee: CALIWAY BIOPHARMACEUTICALS CO., LTD.Inventor: Yu-Fang Ling
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Patent number: 10537548Abstract: The present invention discloses a composition and its pharmaceutical composition for reducing body weight and body fat, and a use of said product The composition comprises epigallocatechin gallate, curcumin, and an excipient, wherein the excipient comprises at least one of glyceryl dibehenate, polyoxyethylene stearates, polysorbate 80 mixture, vitamin E polyethylene glycol succinate, glyceryl monostearate, and oleoyl polyoxyl-6 glycerides, or a combination thereof; the polysorbate 80 mixture comprises polysorbate 80 and magnesium aluminometasilicate. In animal testing where obesity is induced either prior to or during testing, use of the composition of the present invention leads to a significant reduction of body weight and body fat.Type: GrantFiled: March 27, 2018Date of Patent: January 21, 2020Assignee: CALIWAY BIOPHARMACEUTICALS CO., LTD.Inventor: Yu-Fang Ling
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Patent number: 10537605Abstract: Provided is a plant extract composition and a pharmaceutical composition thereof for reducing body weight and body fat, wherein the plant extract composition comprises a green tea extract and a turmeric extract respectively 30 wt % to 75 wt % and 20 wt % to 55 wt % of a total weight of the composition. In diet-induced obesity models, either obesity is induced first or simultaneously with administration, the plant extract composition and a pharmaceutical composition thereof can reduce body weight and body fat more significantly than a single plant extract or commercially available weight loss drugs.Type: GrantFiled: August 28, 2015Date of Patent: January 21, 2020Assignee: CALIWAY BIOPHARMACEUTICALS CO., LTD.Inventor: Yu-Fang Ling
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Patent number: 10226503Abstract: Disclosed in the present invention is the composition for reducing local fat and body weight, and pharmaceuticals and use thereof. The composition contains resveratrol and curcumin extract at a weight ration from 1:30 to 10:1. The composition and pharmaceuticals thereof of the invention can inhibit the growth of fat cells, cause planned apoptosis of fat cells, achieve the effects of reducing fat cells, and reducing local fat deposition and body weight without causing inflammations or necrosis of surrounding cells or tissues and inflammations or pain reactions of surrounding tissues, thereby avoiding the problems of tissue damage and inflammatory pains caused by liposuction or low invasion fat-dissolving apparatus used in the prior art and the problems such as surrounding tissue inflammations and necrosis infections triggered by cell disruption and necrosis caused by components of a fat-dissolving injection, phosphatidylcholine or sodium deoxycholate.Type: GrantFiled: February 23, 2017Date of Patent: March 12, 2019Assignee: CALIWAY BIOPHARMACEUTICALS CO., LTD.Inventor: Yu-Fang Ling
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Patent number: 9987325Abstract: Provided is a composition and a pharmaceutical composition for reducing localized fat or promoting weight loss, wherein the composition comprises a plant extract composition comprising resveratrol and turmeric extract and a weight ratio of resveratrol and turmeric extract ranges from 1:30 to 10:1. The composition and the pharmaceutical composition are primarily administered through localized injection to inhibit the growth of fat cells and promote fat cells apoptosis to reduce adipocytes, decrease localized fat deposition, and promote weight loss, without causing inflammation or necrosis on peripheral cells or tissues to avoid severe pain, so as to avoid inflammation, damage, and pain caused by surgical liposuction or non-surgical lipolysis products such as phosphatidylcholine and sodium deoxycholate.Type: GrantFiled: August 28, 2015Date of Patent: June 5, 2018Assignee: CALIWAY BIOPHARMACEUTICALS CO., LTD.Inventor: Yu-Fang Ling
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Publication number: 20170157193Abstract: Provided is a composition and a pharmaceutical composition for reducing topical fat or promoting weight loss, wherein the composition comprises a plant extract composition comprising resveratrol and turmeric extract and a weight ratio of resveratrol and turmeric extract ranges from 1:30 to 10:1. The composition and the pharmaceutical composition are primarily administered through topical injection to inhibit the growth of fat cells and promote fat cells apoptosis to reduce adipocytes, decrease topical fat deposition, and promote weight loss, without causing inflammation or necrosis on peripheral cells or tissues to avoid severe pain, so as to avoid inflammation, damage, and pain caused by surgical liposuction or non-surgical lipolysis products such as phosphatidylcholine and sodium deoxycholate.Type: ApplicationFiled: August 28, 2015Publication date: June 8, 2017Applicant: CALIWAY BIOPHARMACEUTICALS CO., LTD.Inventor: Yu-Fang Ling