Abstract: Methods and devices for dispensing a therapeutic composition from within a sealed container and drug delivery systems are described. The device and the method for dispensing a therapeutic composition from within a sealed container comprises a container configured to hold a therapeutic composition and include a first septum, a needle, a tube and an expandable membrane configured to expand out of the tube into an interior volume of the container to displace the therapeutic composition out of the container through the needle.

Abstract: Electrochemical systems and methods involving gas generation and/or consumption are generally described. In some aspects, an electrochemical system (e.g., an electrochemical cell) including a first electrode (e.g., an intercalation electrode) and a second electrode (e.g., for gas generation and/or consumption) is provided. Generation and/or consumption of gaseous species may be accomplished in some instances via application of voltages, and in some instances generated gas can deform components of the electrochemical system (e.g., compliant surfaces). The electrode materials may be chosen such that gas generation and/or consumption can be accomplished reversibly, controllably, and/or with relatively small energy input. Such properties may be useful in fluid pumping and/ or valving applications.

Abstract: Electrochemical actuators including a sealed electrolytic chamber with two or more electrodes disposed therein and associated reservoirs are described. In some embodiments, the electrochemical actuators include one or more rigid structures that are overmolded onto one or more electrodes to form the electrolytic chambers. In some embodiments, multiple rigid structures that are overmolded onto two or separate electrodes may be connected to form one or more electrolytic chambers with a desired configuration of electrodes contained therein. Manufacturing methods and structures related to the formation of an array of electrochemical actuators are also described.

Abstract: Infusion pump deployment systems and related methods are described. In one embodiment, after actuation, a cannulation system may simultaneously deploy a cannula of a device into tissue and release the device from the cannulation system. Associated methods and constructions of the cannulation system and devices are also described.

Abstract: Infusion pumps including a plurality of reservoirs arranged either serially and/or in parallel with one another are described. In some embodiments, flow channels with a desired arrangement of flow resistances, bypass flow paths, pressure sensors, and/or meniscus control structures may be included in the infusion pump to provide a desired flow of one or more therapeutic compounds into and/or out from an infusion pump.